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公开(公告)号：US3709367A
公开(公告)日：1973-01-09
申请号：US3709367D
申请日：1970-04-08
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
IPC: A61F20060101 , A61M20060101 , A61M1/00 , A61M1/24 , B01D20060101 , B01D53/22 , B01D63/10 , B01D65/00 , B32B5/26 , F16S3/00 , B01D31/00
CPC classification number: B01D63/10 , B01D61/28 , B01D2313/146
Abstract: A support structure in the form of a foraminous screen netting having an upper plurality of strands arranged in parallel fashion and intersecting at an angle with a lower plurality of strands, also arranged in parallel fashion. Each strand provides a ridge whose apex extends in a direction generally normal to the plane of the screen upon which is supported substantially by line contact a semipermeable dialyzing membrane. Between each ridge is a groove into which extend channels defined in the membrane by the ridges.
Abstract translation: 多孔屏蔽形式的支撑结构，其具有以多个平行的方式并排设置并与下部多个股线成一定角度相交的多个多股线，并且还以平行的方式布置。 每根股线提供一个脊，其顶端沿着大致垂直于筛网的平面的方向延伸，在该平面上基本上由半透膜透析膜线接触而支撑。 在每个脊之间是沟槽，通过脊限制在膜中限定的通道。
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公开(公告)号：US3857785A
公开(公告)日：1974-12-31
申请号：US29872572
申请日：1972-10-18
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
CPC classification number: B01D63/10 , A61M1/16 , B01D61/28 , B01D2313/00 , F16L5/00
Abstract: An artificial kidney apparatus providing a blood compartment which is entirely self-contained within its own structure. The apparatus further provides, in the self-contained assembly, structure to vary the positive pressure within a dialysate chamber and the pressure gradient across the diffusion membrane. Improved connector units provide uniform blood distribution into the diffusion membrane.
Abstract translation: 一种人造肾脏装置，其提供在其自身结构内完全独立的血液隔室。 该装置在独立组件中进一步提供了改变透析液室内的正压力和横跨扩散膜的压力梯度的结构。 改进的连接器单元提供均匀的血液分布到扩散膜。
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3.发明授权Method of making diffusion devices having a membrane support of photoinsolubilized plastic 失效制造具有光催化塑料的薄膜支撑的扩散装置的方法
公开(公告)号：US3753712A
公开(公告)日：1973-08-21
申请号：US3753712D
申请日：1970-11-23
Applicant: BAXTER LABORATORIES INC
Inventor： JANNECK H , MARTINEZ F , SCHNITZIUS G
IPC: A61F20060101 , A61M1/00 , B01D20060101 , B01D65/00 , B01J20060101 , B29D7/00 , C08J20060101 , B01D31/00
CPC classification number: B01D61/30 , B01D2313/14
Abstract: Mass transfer diffusion devices, such as artificial kidneys and membrane oxygenators, are provided having a membrane support which comprises a supporting layer made from photoinsolubilized plastic. The supporting layer defines a plurality of projections of uniform height to support the membrane and to define fluid flow channels of uniform depth between the projections. The membrane support is fabricated by overlaying a photoinsolubilizable plastic layer with a master transparency having transparent and opaque areas disposed in a predetermined arrangement, passing light or other radiation through the transparency to insolubilize appropriate portions of the plastic layer, and then washing away the remaining soluble portions of the plastic layer.
Abstract translation: 提供了质量传递扩散装置，例如人造肾和膜氧合器，其具有膜支撑体，该膜支撑体包括由光致溶性塑料制成的支撑层。 支撑层限定多个均匀高度的突起，以支撑膜并且限定突起之间具有均匀深度的流体流动通道。 通过将具有透明和不透明区域的主透明体覆盖在预定布置上，使光或其它辐射穿过透明物以使不透明的塑料层的适当部分不溶解，然后将剩下的可溶的 部分塑料层。
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Patent Agency Ranking
公开(公告)号：US3743098A
公开(公告)日：1973-07-03
申请号：US3743098D
申请日：1971-12-23
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
IPC: A61M1/14 , A61B20060101 , A61M20060101 , A61M1/00 , A61M1/24 , B01D20060101 , B01D63/10 , B01D31/00
CPC classification number: B01D61/28 , B01D63/10 , B01D2313/146
Abstract: A mass transfer device such as an artificial kidney is disclosed which describes a foraminous screen member supporting and lying against a length of semipermeable membrane of flattened tubular shape. The screen member and membrane are arranged in a spiral about a core, the screen member comprising first and second sets of spaced parallel strands in separate planes. The sets of strands lie against each other and define an angle thereto, and are connected to each other at their crossing points. One of the sets of strands is disposed in longitudinal relation to the axis of the tubular membrane. The strands of the longitudinally arranged set have center lines which are spaced apart from each other by a distance which is preferably at least twice the corresponding spacing distance between the strands of the other set.
Abstract translation: 公开了一种诸如人造肾的传质装置，其描述了支撑并覆盖一段长度为扁平管状的半透膜的多孔屏蔽构件。 屏幕构件和膜以围绕芯的螺旋形布置，屏幕构件包括在分开的平面中的第一组和第二组间隔开的平行线。 线组彼此相对并且限定一个角度，并且在它们的交叉点彼此连接。 一组股线之一与管状膜的轴线成纵向配置。 纵向布置的组的绞线具有彼此间隔开一段距离的中心线，该距离优选地是另一组的绞线之间的相应间隔距离的至少两倍。
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公开(公告)号：US3814137A
公开(公告)日：1974-06-04
申请号：US32673773
申请日：1973-01-26
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
CPC classification number: A61M39/04
Abstract: An injection site for a flow conduit for biological fluids and the like, such as blood or parenteral solutions, is provided having improved resistance to leakage through needle punctures, even when the pressure within the flow conduit is substantially different from the pressure outside of the conduit. The conduit comprises tubing made of a biologically compatible material, in which a portion of the tubing is surrounded by an elastomeric sleeve injection site. A second elastic sleeve surrounds the first elastomeric sleeve, the second sleeve having an unstretched inner diameter which is less than the outer diameter of the elastomeric sleeve. As a result, the elastomeric sleeve is compressed by the second sleeve, whereby the sealing of the elastomeric sleeve after puncture by a needle is improved.
Abstract translation: 提供用于生物流体等的流动管道的注射部位，例如血液或肠胃外溶液，其具有通过针穿刺的泄漏的改善的抗性，即使当流动导管内的压力与导管外部的压力基本上不同时 。 导管包括由生物相容的材料制成的管，其中一部分管被弹性体套筒注射部位包围。 第二弹性套筒环绕第一弹性体套筒，第二套筒具有小于弹性套筒的外径的未拉伸内径。 结果，弹性体套筒被第二套筒压缩，从而改善了针穿刺后弹性体套筒的密封。
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6.发明授权Bubble trap for removal of bubbles from biological fluids under sterile conditions 失效用于从无菌条件下的生物流体中除去泡罩的气泡
公开(公告)号：US3778973A
公开(公告)日：1973-12-18
申请号：US3778973D
申请日：1971-12-23
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
CPC classification number: A61M5/36 , A61M1/3627
Abstract: A bubble trap for liquid flowing in a conduit comprises an inlet port communicating with one end of a first chamber. The other end of the first chamber is closed, and a lateral port is defined in the side of the first chamber, communicating with the side of a second chamber between the ends thereof. The second chamber has an outlet port at an end opposite the inlet port, and a bubble collection port at an end adjacent the inlet port. The bubble collection port is closed with a resealable diaphragm, to permit the repeated aseptic insertion of a syringe to remove trapped gas.
Abstract translation: 用于在管道中流动的液体的气泡阱包括与第一室的一端连通的入口。 第一腔室的另一端是封闭的，并且在第一腔室的侧面中限定了一个侧面端口，与第二腔室的两端之间的第二腔室的一侧相通。 第二室具有在与入口相对的一端的出口，以及在靠近入口端的端部处的气泡收集口。 气泡收集口用可重新密封的隔膜封闭，以允许反复无菌地插入注射器以除去被截留的气体。
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公开(公告)号：US3712475A
公开(公告)日：1973-01-23
申请号：US3712475D
申请日：1970-08-31
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
CPC classification number: B01D63/10 , A61M1/16 , A61M2205/3331 , B01D61/28 , B01D61/32 , B01D2313/18 , B01D2313/21
Abstract: A cover for sealingly closing the dialysate chamber of an extracorporeal kidney apparatus and providing a flow duct for passing dialyzing fluid from the chamber. A valve in said flow duct to adjust the flow (volume/time) and vary the pressure within the dialyzing fluid compartment.
Abstract translation: 一种用于密封关闭体外肾脏装置的透析液室并提供用于使来自腔室的透析液体流过的流动管道的盖子。 所述流道中的阀，用于调节流量（体积/时间）并改变透析流体隔室内的压力。
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公开(公告)号：US3712474A
公开(公告)日：1973-01-23
申请号：US3712474D
申请日：1970-04-08
Applicant: BAXTER LABORATORIES INC
Inventor： MARTINEZ F
CPC classification number: B01D61/28 , B01D63/10 , B01D2313/00 , F16L5/10 , F16L47/065
Abstract: An artificial kidney apparatus providing a blood compartment which is entirely self-contained within its own structure. The apparatus further provides, in the self-contained assembly, structure to vary the positive pressure within a dialysate chamber and the pressure gradient across the diffusion membrane. Improved connector units provide uniform blood distribution into the diffusion membrane.
Abstract translation: 一种人造肾脏装置，其提供在其自身结构内完全独立的血液隔室。 该装置在独立组件中进一步提供了改变透析液室内的正压力和横跨扩散膜的压力梯度的结构。 改进的连接器单元提供均匀的血液分布到扩散膜。
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