公开(公告)号：US3660405A

公开(公告)日：1972-05-02

申请号：US3660405D

申请日：1969-08-13

Applicant: BAXTER LABORATORIES INC

Inventor： BERGER ARTHUR ,  BORGAES EDELTRAUT E

IPC: C07D513/04 ,  C07D51/46

CPC classification number: C07D513/04

Abstract: THIAZOLOPYRIMIDINES HAVING THE GENERAL FORMULA:

2-(R-NH-),4,6-DI(CH3-)-THIAZOLO(4,5-D)PYRIMIDINE-5(4H),

7(6H)-DIONE

WHEREIN R IS SELECTED FROM THE GROUP CONSISTING OF LOWER ALKYL HAVING FROM 1 TO 4 CARBON ATOMS AND ALLYL, FOR EXAMPLE, 4,6-DIMETHYL - 2 - N-PROPYLAMINOTHIAZOLO-(4,5-D)PYRIMIDINE 5,7,DIONE. THESE COMPOUNDS ARE USEFUL CENTRAL NERVOUS SYSTEM ANTI-DEPRESANTS.

公开(公告)号：US3637703A

公开(公告)日：1972-01-25

申请号：US3637703D

申请日：1969-08-13

Applicant: BAXTER LABORATORIES INC

Inventor： BERGER ARTHUR ,  BORGAES EDELTRAUT E

IPC: A61K31/505 ,  C07D239/54 ,  C07D239/545 ,  C07D51/30

CPC classification number: C07D239/545 ,  A61K31/505

Abstract: URACIL THIPSEUDOUREAS HAVING THE GENERAL FORMULA:

1,3-DI(CH3-),2,6-DI(O=),4-(R-NH-C(-S-R'')=N-)HEXAHYDRO

PYRIMIDINE

WHEREIN R AND R'' ARE EACH INDEPENDENTLY SELECTED FROM THE GROUP CONSISTING OF LOWER ALKYL HAVING FROM 1 TO 3 CARBON ATOMS, ALLYL AND METHALLYL, AND THE PHARMACEUTICALLY ACCEPTABLE ACID SALTS THEREOF, FOR EXAMPLE, 1-ALLYL3-(2'',4''-DIKETO - 1'',2'',3'',4''-TETRAHYDROPYRIMIDIN-6-YL)-1'',2, 3''-TRIMETHYL-2-THIOPSEUDOUREA. THESE COMPOUNDS ARE USEFUL CENTRAL NERVOUS SYSTEM ANTI-DEPRESSANTS.

公开(公告)号：US3506680A

公开(公告)日：1970-04-14

申请号：US3506680D

申请日：1968-01-18

Applicant: BAXTER LABORATORIES INC

Inventor： BERGER ARTHUR ,  BORGAES EDELTRAUT E ,  LONGSTREET JOHN C

IPC: A61K31/155 ,  A01N9/20 ,  A01N9/24

CPC classification number: A61K31/155