公开(公告)号：US20210388014A1

公开(公告)日：2021-12-16

申请号：US17286474

申请日：2019-10-17

Applicant: BASF SE

Inventor： Michael PUHL ,  Sebastian WLOCH ,  Peter OEDMAN ,  Anne-Catrin LETZEL ,  Hartwing SCHROEDER ,  Jacek MALISZ ,  Daniel SEIBERT-LUDWIG ,  Emiel Jan KAPPERT ,  Chung Huan WONG ,  Michael BARROS GROSS ,  Martin VIERTELHAUS

IPC: C07H1/08 ,  C07H3/06

Abstract: The present invention relates to a method for obtaining crystalline 2′-fucosyllactose from a 2′-FL raw material, which contains 2′-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2′-FL, where the method comprises a)providing a solution of the 2′-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2′-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2′-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).