公开(公告)号：US20240075027A1

公开(公告)日：2024-03-07

申请号：US18320470

申请日：2023-05-19

申请人： Auburn University

发明人： Amit Kumar Mitra ,  Harish Kumar

IPC分类号： A61K31/498 ,  A61K31/454 ,  A61K31/69 ,  A61K38/05 ,  A61K38/06 ,  A61K38/07 ,  A61P35/00

CPC分类号： A61K31/498 ,  A61K31/454 ,  A61K31/69 ,  A61K38/05 ,  A61K38/06 ,  A61K38/07 ,  A61P35/00

摘要： The present invention relates to compositions comprising clofazimine and methods for treating cancer. In various embodiments, the compositions and methods further comprise a proteasome inhibitor and/or immunomodulatory drug. The compositions and methods of the present invention may be used for naïve cancers as well as those that have developed resistance to proteasome inhibitors and/or immunomodulatory drugs.