公开(公告)号：US20140221443A1

公开(公告)日：2014-08-07

申请号：US14152766

申请日：2014-01-10

Applicant: Astrazeneca AB ,  Array BioPharma Inc.

Inventor： John DeMattei ,  Tsung-Hsun Chuang ,  Gorkhn Sharma-Singh ,  Paul Alfred Dickinson ,  Mohammed Pervez ,  Richard Anthony Storey ,  Christopher John Squire ,  James Gair Ford ,  Ronald John Roberts

IPC: C07D235/08

CPC classification number: C07D235/08 ,  C07D235/06

Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.

Abstract translation: 本发明涉及化合物1硫酸氢盐和溶剂合物，其结晶形式和无定形形式，以及其制备方法。

公开(公告)号：US20160024018A1

公开(公告)日：2016-01-28

申请号：US14698151

申请日：2015-04-28

Applicant: Array BioPharma Inc. ,  ASTRAZENECA R&D ALDERLEY

Inventor： John DeMattei ,  Tsung-Hsun Chuang ,  Gorkhn Sharma-Singh ,  Paul Alfred Dickinson ,  Mohammed Pervez ,  Richard Anthony Storey ,  Christopher John Squire ,  James Gair Ford ,  Ronald John Roberts

IPC: C07D235/08

CPC classification number: C07D235/08 ,  C07D235/06

Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.

Abstract translation: 本发明涉及化合物1硫酸氢盐和溶剂合物，其结晶形式和无定形形式，以及其制备方法。

公开(公告)号：US09562017B2

公开(公告)日：2017-02-07

申请号：US14698151

申请日：2015-04-28

Applicant: Array BioPharma Inc. ,  ASTRAZENECA R&D ALDERLEY

Inventor： John DeMattei ,  Tsung-Hsun Chuang ,  Gorkhn Sharma-Singh ,  Paul Alfred Dickinson ,  Mohammed Pervez ,  Richard Anthony Storey ,  Christopher John Squire ,  James Gair Ford ,  Ronald John Roberts

IPC: C07D235/08 ,  C07D235/06

CPC classification number: C07D235/08 ,  C07D235/06

Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.

Abstract translation: 本发明涉及化合物1硫酸氢盐和溶剂合物，其结晶形式和无定形形式，以及其制备方法。 化合物I