公开(公告)号：US20230159451A1

公开(公告)日：2023-05-25

申请号：US17806371

申请日：2022-06-10

Applicant: Ascletis BioScience Co., Ltd.

Inventor： Bailing YANG ,  Bin LIANG ,  Yang LAI ,  Jinzi J. WU

IPC: C07D207/27 ,  C07D403/14 ,  C07D417/14 ,  C07D487/08 ,  C07D493/08 ,  C07D405/14 ,  C07D409/14 ,  C07D471/04 ,  A61P31/14

CPC classification number: C07D207/27 ,  C07D403/14 ,  C07D417/14 ,  C07D487/08 ,  C07D493/08 ,  C07D405/14 ,  C07D409/14 ,  C07D471/04 ,  A61P31/14

Abstract: Certain anti-viral compounds, pharmaceutical compositions, and methods related thereto are disclosed.

公开(公告)号：US20240189337A1

公开(公告)日：2024-06-13

申请号：US18519961

申请日：2023-11-27

Applicant: ASCLETIS BIOSCIENCE CO., LTD.

Inventor： Bin LIANG ,  Bailing YANG ,  Yang LAI ,  Jinzi Jason WU

IPC: A61K31/7084 ,  A61K45/06 ,  A61P31/12 ,  A61P35/00 ,  C07H21/02

CPC classification number: A61K31/7084 ,  A61K45/06 ,  A61P31/12 ,  A61P35/00 ,  C07H21/02

Abstract: Certain anti-viral compounds, pharmaceutical compositions, and methods related thereto are disclosed.

公开(公告)号：US20240270756A1

公开(公告)日：2024-08-15

申请号：US18416152

申请日：2024-01-18

Applicant: Ascletis BioScience Co., Ltd.

Inventor： Jinzi Jason WU ,  Bin LIANG

IPC: C07D498/14 ,  A61K31/4985 ,  A61K31/5383

CPC classification number: C07D498/14 ,  A61K31/4985 ,  A61K31/5383

Abstract: Disclosed are a compound of Formula I, stereoisomers, pharmaceutically acceptable salts and deuterated compounds thereof and a method for treating, inhibiting and/or preventing a disease or disorder in a subject in need thereof:




wherein A, R, G, Y and n are defined as in the present disclosure.

公开(公告)号：US20230234921A1

公开(公告)日：2023-07-27

申请号：US18191523

申请日：2023-03-28

Applicant: Ascletis BioScience Co., Ltd.

Inventor： Bailing YANG ,  Bin LIANG ,  Yang LAI ,  Jinzi Jason WU

IPC: C07D207/27 ,  C07D405/14 ,  C07D471/04 ,  C07D409/14 ,  A61P31/14 ,  C07D487/08 ,  C07D403/14 ,  C07D417/14 ,  C07D493/08

CPC classification number: C07D207/27 ,  C07D405/14 ,  C07D471/04 ,  C07D409/14 ,  A61P31/14 ,  C07D487/08 ,  C07D403/14 ,  C07D417/14 ,  C07D493/08

Abstract: Certain anti-viral compounds, pharmaceutical compositions, and methods related thereto are disclosed.

公开(公告)号：US20240327428A1

公开(公告)日：2024-10-03

申请号：US18585050

申请日：2024-02-22

Applicant: ASCLETIS BIOSCIENCE CO., LTD.

Inventor： Jinzi Jason WU ,  Bin LIANG ,  Bailing YANG

IPC: C07D513/04 ,  A61K31/4355 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4439 ,  A61K31/519 ,  A61K31/53 ,  A61K31/5377 ,  A61K45/06 ,  A61P31/18 ,  C07D401/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/04 ,  C07D519/00

CPC classification number: C07D513/04 ,  A61K31/4355 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4439 ,  A61K31/519 ,  A61K31/53 ,  A61K31/5377 ,  A61K45/06 ,  A61P31/18 ,  C07D401/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07D498/04 ,  C07D519/00

Abstract: The present application describes compounds of capsid inhibitors that are useful for treating HIV infection in a human. One aspect of the present application relates to a compound of Formula I, stereoisomers thereof, pharmaceutically acceptable salts thereof, or deuterium substitutes thereof as described in the present disclosure.

公开(公告)号：US20230190782A1

公开(公告)日：2023-06-22

申请号：US18046339

申请日：2022-10-13

Applicant: Ascletis BioScience Co., Ltd

Inventor： Bin LIANG ,  Bailing Yang ,  Yang Lai ,  Jinzi Jason Wu

IPC: A61K31/7084 ,  A61P35/00 ,  C07H21/02 ,  A61P31/12 ,  A61K45/06

CPC classification number: A61K31/7084 ,  A61P35/00 ,  C07H21/02 ,  A61P31/12 ,  A61K45/06

Abstract: Certain anti-viral compounds, pharmaceutical compositions, and methods related thereto are disclosed.