公开(公告)号：US20170087156A1

公开(公告)日：2017-03-30

申请号：US15311148

申请日：2015-05-14

Applicant: Array BioPharma Inc.

Inventor： Shelley Allen ,  Steven W. Andrews ,  Brian Baer ,  Zackary Crane ,  Weidong Liu ,  Daniel John Watson

IPC: A61K31/506 ,  A61K9/00 ,  C07D207/16 ,  C07D403/14 ,  A61K45/06

CPC classification number: A61K31/506 ,  A61K9/0053 ,  A61K45/06 ,  C07D207/16 ,  C07D401/14 ,  C07D403/12 ,  C07D403/14 ,  C07D405/14

Abstract: Provided is Compound (I) or a pharmaceutically acceptable salt thereof, which is an inhibitor of TrkA kinase and is useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation and inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome, diseases related to an imbalance of the regulation of bone remodeling, and diseases resulting from Connective Tissue Growth Factor aberrant signaling.