-
![Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors](/abs-image/US/2019/01/08/US10174027B2/abs.jpg.150x150.jpg)
公开(公告)号：US10174027B2
公开(公告)日：2019-01-08
申请号：US15858658
申请日：2017-12-29
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors](/abs-image/US/2019/01/08/US10174028B2/abs.jpg.150x150.jpg)
公开(公告)号：US10174028B2
公开(公告)日：2019-01-08
申请号：US15860849
申请日：2018-01-03
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2018/07/05/US20180186790A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180186790A1
公开(公告)日：2018-07-05
申请号：US15858658
申请日：2017-12-29
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/55 , A61K45/06 , A61K31/499 , A61K31/444 , A61K31/5377 , A61K31/496 , A61K31/497 , C07D519/00 , A61K31/506 , A61K31/4545
CPC classification number: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors](/abs-image/US/2018/07/17/US10023570B2/abs.jpg.150x150.jpg)
公开(公告)号：US10023570B2
公开(公告)日：2018-07-17
申请号：US15211702
申请日：2016-07-15
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2018/07/05/US20180186791A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180186791A1
公开(公告)日：2018-07-05
申请号：US15860781
申请日：2018-01-03
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/55 , A61K45/06 , A61K31/499 , A61K31/444 , A61K31/5377 , A61K31/496 , A61K31/497 , C07D519/00 , A61K31/506 , A61K31/4545
CPC classification number: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
Patent Agency Ranking
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2018/06/28/US20180179203A1/abs.jpg.150x150.jpg)
公开(公告)号：US20180179203A1
公开(公告)日：2018-06-28
申请号：US15860849
申请日：2018-01-03
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/55 , A61K45/06 , A61K31/499 , A61K31/444 , A61K31/5377 , A61K31/496 , A61K31/497 , C07D519/00 , A61K31/506 , A61K31/4545
CPC classification number: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2019/05/02/US20190127375A1/abs.jpg.150x150.jpg)
公开(公告)号：US20190127375A1
公开(公告)日：2019-05-02
申请号：US16245004
申请日：2019-01-10
Applicant: Array BioPharma Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/5377 , A61K31/506 , C07D519/00 , A61K31/497 , A61K31/55 , A61K31/4545 , A61K31/444 , A61K31/499 , A61K45/06 , A61K31/496
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2019/05/02/US20190127374A1/abs.jpg.150x150.jpg)
公开(公告)号：US20190127374A1
公开(公告)日：2019-05-02
申请号：US16241839
申请日：2019-01-07
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/55 , A61K45/06 , A61K31/499 , A61K31/444 , A61K31/5377 , A61K31/496 , A61K31/497 , C07D519/00 , A61K31/506 , A61K31/4545
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS](/abs-image/US/2019/05/02/US20190127373A1/abs.jpg.150x150.jpg)
公开(公告)号：US20190127373A1
公开(公告)日：2019-05-02
申请号：US16241837
申请日：2019-01-07
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/55 , A61K45/06 , A61K31/499 , A61K31/444 , A61K31/5377 , A61K31/496 , A61K31/497 , C07D519/00 , A61K31/506 , A61K31/4545
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
![Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors](/abs-image/US/2018/11/27/US10138243B2/abs.jpg.150x150.jpg)
公开(公告)号：US10138243B2
公开(公告)日：2018-11-27
申请号：US15860781
申请日：2018-01-03
Applicant: Array BioPharma, Inc.
Inventor： Steven W. Andrews , James F. Blake , Mark J. Chicarelli , Adam Golos , Julia Haas , Yutong Jiang , Gabrielle R. Kolakowski
IPC: C07D471/04 , A61K31/444 , A61K31/4545 , A61K31/496 , A61K31/497 , A61K31/499 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K45/06 , C07D519/00
Abstract: Provided herein are compounds of the General Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, D, E, X1, X2, X3 and X4 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including diseases or disorders mediated by a RET kinase.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.052 seconds)
