公开(公告)号：US11058824B2

公开(公告)日：2021-07-13

申请号：US16389336

申请日：2019-04-19

申请人： Antares Pharma, Inc.

发明人： Janice L. Cox ,  Matthew H. Rust ,  Thomas E. Kramer ,  Peter A. Hoeft

IPC分类号： A61M5/315 ,  A61M5/24 ,  A61M5/31

摘要： A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

公开(公告)号：US10300212B2

公开(公告)日：2019-05-28

申请号：US15376726

申请日：2016-12-13

申请人： Antares Pharma, Inc.

发明人： Janice L. Cox ,  Matthew H. Rust ,  Thomas E. Kramer ,  Peter A. Hoeft

IPC分类号： A61M5/315 ,  A61M5/24 ,  A61M5/31

摘要： A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

公开(公告)号：US09561333B2

公开(公告)日：2017-02-07

申请号：US14568857

申请日：2014-12-12

申请人： Antares Pharma, Inc.

发明人： Janice L. Cox ,  Matthew H. Rust ,  Thomas E. Kramer ,  Peter A. Hoeft

IPC分类号： A61M5/315 ,  A61M5/24 ,  A61M5/31

CPC分类号： A61M5/31593 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/31541 ,  A61M5/31545 ,  A61M5/31566 ,  A61M5/3158 ,  A61M2005/2403 ,  A61M2005/2407

摘要： A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

摘要翻译： 公开了一种药物分配机构，其配置成从药物室喷射连续剂量的药物。 分配机构的一个实施例包括壳体和构造成从腔室喷出剂量的药剂的柱塞杆。 分配机构还包括致动机构，其包括与壳体相关联的触发器，并且具有相对于其的就绪和被击发位置。 触发器构造成用于由用户操作以便从准备位置到触发位置的大致轴向的计量运动中连续运动，在该位置触发器与柱塞杆相关联，以使柱塞杆弹出预定的一个剂量中的一个 体积和从点火位置到包括轴向旋转的就绪位置的复位运动，其中在复位运动期间触发器与柱塞杆脱离。

公开(公告)号：US09364610B2

公开(公告)日：2016-06-14

申请号：US13889183

申请日：2013-05-07

申请人： ANTARES PHARMA, INC.

发明人： Thomas KraMer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski

IPC分类号： A61M5/20 ,  A61M5/30 ,  A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/20 ,  A61M5/2053 ,  A61M5/30 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/208 ,  A61M2005/3125 ,  A61M2202/0007 ,  A61M2202/048

摘要： An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

摘要翻译： 喷射器的示例性实施例包括触发机构，能量源和用户可操作的起火构件。 触发器构件可以包括具有保持器部分的触发器构件，以及具有构造成对药物容器进行加压以从其中排出药物的冲头的冲头组件，以及触发器接合构件，其构造成以预定位置接合触发构件的保持器部分， 点火条件。 能量源可以与冲头相关联，以驱动冲头以排出药物，并且用户可操作的起火构件可操作用于在触发器接合构件和保持器部分之间从预燃烧状态引起轴向旋转 到触发接合构件从保持器部分释放以允许能量源对冲头起动的点火状态。

公开(公告)号：US20130331788A1

公开(公告)日：2013-12-12

申请号：US13889183

申请日：2013-05-07

申请人： ANTARES PHARMA, INC.

发明人： Thomas KraMer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/20 ,  A61M5/2053 ,  A61M5/30 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/208 ,  A61M2005/3125 ,  A61M2202/0007 ,  A61M2202/048

摘要： An exemplary embodiment of injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

摘要翻译： 喷射器的示例性实施例包括触发机构，能量源和用户可操作的起火构件。 触发器构件可以包括具有保持器部分的触发器构件，以及具有构造成对药物容器进行加压以从其中排出药物的冲头的冲头组件，以及触发器接合构件，其构造成以预定的方式与触发器构件的保持器部分接合， 点火条件。 能量源可以与冲头相关联，以驱动冲头以排出药物，并且用户可操作的起火构件可操作用于在触发器接合构件和保持器部分之间从预燃烧状态引起轴向旋转 到触发接合构件从保持器部分释放以允许能量源对冲头起动的点火状态。

公开(公告)号：US20220080131A1

公开(公告)日：2022-03-17

申请号：US17536954

申请日：2021-11-29

申请人： Antares Pharma, Inc.

发明人： Thomas E. Kramer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski

IPC分类号： A61M5/50 ,  A61M5/30 ,  A61M5/32 ,  A61M5/20

摘要： An exemplary embodiment of the present disclosure can provide an injector including a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

公开(公告)号：US10279131B2

公开(公告)日：2019-05-07

申请号：US15234345

申请日：2016-08-11

申请人： Antares Pharma, Inc.

发明人： Thomas E. Kramer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski

IPC分类号： A61M5/20 ,  A61M5/30 ,  A61M5/32 ,  A61M5/50

摘要： An exemplary embodiment of the present disclosure can provide an injector including a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger member can include a trigger member having a retainer portion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom and a trigger engagement member configured to engage the retainer portion of the trigger member in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation between the trigger engagement member and the retainer portion from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retainer portion to allow the energy source to fire the ram.

公开(公告)号：US20170087307A1

公开(公告)日：2017-03-30

申请号：US15376726

申请日：2016-12-13

申请人： Antares Pharma, Inc.

发明人： Janice L. Cox ,  Matthew H. Rust ,  Thomas E. Kramer ,  Peter A. Hoeft

IPC分类号： A61M5/315 ,  A61M5/24

CPC分类号： A61M5/31593 ,  A61M5/24 ,  A61M5/3129 ,  A61M5/31541 ,  A61M5/31545 ,  A61M5/31566 ,  A61M5/3158 ,  A61M2005/2403 ,  A61M2005/2407

摘要： A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.

公开(公告)号：US09364611B2

公开(公告)日：2016-06-14

申请号：US13889190

申请日：2013-05-07

申请人： ANTARES PHARMA, INC.

发明人： Thomas KraMer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski ,  Michael Travanty ,  Patrick Madsen

IPC分类号： A61M5/20 ,  A61M5/30 ,  A61M5/32

CPC分类号： A61M5/2033 ,  A61M5/20 ,  A61M5/2053 ,  A61M5/30 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/208 ,  A61M2005/3125 ,  A61M2202/0007 ,  A61M2202/048

摘要： An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

摘要翻译： 喷射器的示例性实施例包括触发机构，能量源和用户可操作的起火元件。 触发器机构可以包括具有保持部分的浮动触发器构件，具有构造成对药物容器施加压力以从其中排出药物的压头的柱塞组件，柱塞组件还具有浮动触发器接合构件， 当浮动触发元件处于预触发状态时，浮动触发元件。 能量源可以与冲头相关联，用于为冲压器提供动力以排出药剂，并且用户可操作的起火构件可操作用于使浮动触发构件从预燃状态轴向旋转到点火状态 其中浮动触发器接合构件从保持部分释放以允许能量源对冲头进行点火。

公开(公告)号：US20130317431A1

公开(公告)日：2013-11-28

申请号：US13889190

申请日：2013-05-07

申请人： ANTARES PHARMA, INC.

发明人： Thomas KraMer ,  Matthew H. Rust ,  Paul M. Goudreau ,  Peter A. Hoeft ,  Julius C. Sund ,  Peter L. Sadowski ,  Michael Travanty ,  Patrick Madsen

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/20 ,  A61M5/2053 ,  A61M5/30 ,  A61M5/326 ,  A61M5/5086 ,  A61M2005/2013 ,  A61M2005/2026 ,  A61M2005/208 ,  A61M2005/3125 ,  A61M2202/0007 ,  A61M2202/048

摘要： An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

摘要翻译： 喷射器的示例性实施例包括触发机构，能量源和用户可操作的起火元件。 触发器机构可以包括具有保持部分的浮动触发器构件，具有构造成对药物容器施加压力以从其中排出药物的压头的柱塞组件，柱塞组件还具有浮动触发器接合构件， 当浮动触发元件处于预触发状态时，浮动触发元件。 能量源可以与冲头相关联，用于为冲压器提供动力以排出药剂，并且用户可操作的起火构件可操作用于使浮动触发构件从预燃状态轴向旋转到点火状态 其中浮动触发器接合构件从保持部分释放以允许能量源对冲头进行点火。