公开(公告)号：US20220098279A1

公开(公告)日：2022-03-31

申请号：US17426886

申请日：2020-01-29

Applicant: Amgen Inc.

Inventor： Quanzhou LUO ,  Scott KUHNS ,  Diana WOEHLE ,  Matthew JERUMS ,  XueJun HAN ,  Kelli M.G. MATTHIES

IPC: C07K14/71 ,  C07K1/16

Abstract: The present disclosure relates to aflibercept, in particular, attributes of aflibercept. Also provided herein are methods of characterizing and modifying the attributes of aflibercept and compositions comprising aflibercept with particular attributes.

公开(公告)号：US20240417442A1

公开(公告)日：2024-12-19

申请号：US18798878

申请日：2024-08-09

Applicant: Amgen Inc.

Inventor： Quanzhou LUO ,  Scott KUHNS ,  Diana WOEHLE ,  Matthew JERUMS ,  XueJun HAN ,  Kelli M.G. MATTHIES

IPC: C07K14/71 ,  C07K1/16

Abstract: The present disclosure relates to aflibercept, in particular, attributes of aflibercept. Also provided herein are methods of characterizing and modifying the attributes of aflibercept and compositions comprising aflibercept with particular attributes.