公开(公告)号：US10465009B2

公开(公告)日：2019-11-05

申请号：US14649469

申请日：2013-12-05

Applicant: Amgen Inc.

Inventor： Richard J. Armitage ,  Michelle Blake ,  William C. Fanslow, III ,  Jason Charles O'Neill ,  Gunasekaran Kannan ,  Jiangchun Xu ,  Mark Edward Tometsko ,  Zhulun Wang ,  Athena Sudom

IPC: C07K16/28 ,  A61K47/48 ,  A61K45/06 ,  A61N5/10 ,  A61K47/68 ,  A61K39/00

Abstract: The present invention relates to BCMA (B-Cell Maturation Antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to BCMA antibody drug conjugates and uses thereof.