公开(公告)号：US11857543B2

公开(公告)日：2024-01-02

申请号：US14897849

申请日：2014-06-04

Applicant: Akebia Therapeutics, Inc.

Inventor： Robert Shalwitz ,  Charlotte Hartman ,  Akshay Buch ,  Isaiah Shalwitz ,  John Janusz ,  Joseph Gardner

IPC: A61K31/44 ,  A61K31/4412 ,  A61K9/00 ,  A61K33/26 ,  A61K38/18

CPC classification number: A61K31/44 ,  A61K9/0053 ,  A61K31/4412 ,  A61K33/26 ,  A61K38/1816

Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.

公开(公告)号：US20240335434A1

公开(公告)日：2024-10-10

申请号：US18511042

申请日：2023-11-16

Applicant: Akebia Therapeutics, Inc.

Inventor： Robert Shalwitz ,  Charlotte Hartman ,  Akshay Buch ,  Isaiah Shalwitz ,  John Janusz ,  Joseph Gardner

IPC: A61K31/44 ,  A61K9/00 ,  A61K31/4412 ,  A61K33/26 ,  A61K38/18

CPC classification number: A61K31/44 ,  A61K9/0053 ,  A61K31/4412 ,  A61K33/26 ,  A61K38/1816

Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.

公开(公告)号：US20160143891A1

公开(公告)日：2016-05-26

申请号：US14897849

申请日：2014-06-04

Applicant: AKEBIA THERAPEUTICS, INC.

Inventor： Robert Shalwitz ,  Charlotte Hartman ,  Akshay Buch ,  Isaiah Shalwitz ,  John Janusz ,  Joseph Gardner

IPC: A61K31/44 ,  A61K9/00 ,  A61K38/18 ,  A61K33/26

CPC classification number: A61K31/44 ,  A61K9/0053 ,  A61K31/4412 ,  A61K33/26 ,  A61K38/1816

Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.

Abstract translation: 本文提供了使用HIF脯氨酰羟化酶抑制剂治疗或预防贫血的特定剂量和给药方案，例如继发于慢性肾脏疾病的贫血或与化疗相关的贫血或与AIDS相关的贫血。