专利检索 ap:("Active Biotech AB") AND inv:"Marie Bainbridge" 第 1 页

1.

发明授权
Imidazo[2,1-B]thiazole and 5,6-dihydroimidazo[2,1-B]thiazole derivatives useful as S100-inhibitors 有权

公开(公告)号：US10385069B2

公开(公告)日：2019-08-20

申请号：US15545573

申请日：2015-12-04

申请人： Active Biotech AB

发明人： Ulf Wellmar , Stephen East , Marie Bainbridge , Colin MacKinnon , James Carr , Jonathan Hargrave

IPC分类号： C07D513/04 , C07D513/14

摘要： A compound of formula (I) or a pharmaceutically acceptable salt thereof. The compound is useful for use in the treatment of cancer, an inflammatory disorder, an autoimmunity disorder or a neurodegenerative disorder.

2.

发明授权
Compounds useful as S100-inhibitors 有权

公开(公告)号：US09771372B2

公开(公告)日：2017-09-26

申请号：US15312762

申请日：2015-05-22

申请人： Active Biotech AB

发明人： Ulf Wellmar , David Liberg , Maria Ekblad , Marie Bainbridge , Stephen East , Jonathan Hargrave , Natacha Prevost

IPC分类号： C07D487/04

CPC分类号： C07D487/04

摘要： A compound of formula (I) or a pharmaceutically acceptable salt thereof and a pharmaceutical composition comprising the compound. The compound is an inhibitor of interactions between S100A9 and interaction partners such as RAGE, TLR4 and EMMPRIN and as such is useful in the treatment of disorders such as cancer, autoimmune disorders, inflammatory disorders and neurodegenerative disorders.