公开(公告)号：US09750707B2

公开(公告)日：2017-09-05

申请号：US14255630

申请日：2014-04-17

申请人： Acorda Therapeutics, Inc.

发明人： Naweed Muhammad ,  Gene Curtis Jamieson ,  Keith R. Bley ,  Sanjay Chanda

IPC分类号： A61F13/00 ,  A61K31/165 ,  A61K9/00 ,  A61K9/08 ,  A61K9/107 ,  A61K9/127 ,  A61K47/08 ,  A61K47/10 ,  A61K45/06 ,  A61K47/12

CPC分类号： A61K31/165 ,  A61K9/0014 ,  A61K9/08 ,  A61K9/1075 ,  A61K9/127 ,  A61K45/06 ,  A61K47/08 ,  A61K47/10 ,  A61K47/12

摘要： Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.