公开(公告)号：US20240307331A1

公开(公告)日：2024-09-19

申请号：US18173743

申请日：2021-08-23

Applicant: Abrexa Pharmaceuticals, Inc. ,  The Penn State Research Foundation

Inventor： Jesus E. VILLAFRANCA ,  Charles Richard KISSINGER ,  Guohong LI

IPC: A61K31/167 ,  A61K38/48 ,  A61P7/04 ,  A61P9/10

CPC classification number: A61K31/167 ,  A61K38/482 ,  A61P7/04 ,  A61P9/10 ,  C12Y304/21068

Abstract: Hemorrhage and vascular instability can be induced by thrombolytic and anti-coagulant therapies. Presented herein, in certain aspects, are methods for the treatment and/or prevention of hemorrhage and vascular instability that comprise administering a compound disclosed herein to a subject in need thereof.