公开(公告)号：US20240300936A1

公开(公告)日：2024-09-12

申请号：US18568365

申请日：2022-06-09

Applicant: AVELOS THERAPEUTICS INC.

Inventor： Ki Seon BAEK ,  Ja Heouk KHOO ,  Soongyu CHOI ,  Young Whan PARK ,  Simon WARD ,  Darren LE GRAND ,  Ryan WEST ,  Penelope TURNER ,  Samuele MARAMAI ,  Tristan REUILLON

IPC: C07D413/14 ,  A61K31/506 ,  A61K31/53 ,  A61K31/5377 ,  A61P35/00 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D405/14 ,  C07D417/14 ,  C07D471/04 ,  C07D513/04

CPC classification number: C07D413/14 ,  A61K31/506 ,  A61K31/53 ,  A61K31/5377 ,  A61P35/00 ,  C07D401/14 ,  C07D403/04 ,  C07D403/14 ,  C07D405/14 ,  C07D417/14 ,  C07D471/04 ,  C07D513/04

Abstract: This invention relates to compounds which are microtubule associated serine/threonine-like kinase (MASTL) inhibitors and the use of the compounds in the treatment of diseases and medical conditions mediated by MASTL, for example in the treatment of cancer and other target related diseases.