公开(公告)号：US11318178B2

公开(公告)日：2022-05-03

申请号：US17050971

申请日：2019-06-10

Applicant: ATOGEN CO., LTD

Inventor： Bo Ram Beck ,  Ji Hee Kang ,  Gun Seok Park ,  Sung Hoon Im ,  Do Yeun Jeong ,  Yong Hyun Lee

IPC: A61K35/747 ,  A23L33/135

Abstract: A Lactobacillus reuteri ATG-F4 strain (Accession number KCTC13717BP) is proposed. The strain has the function of enhancing dopamine secretion, and thus can be used as a pharmaceutical composition or a functional health food for the prevention or amelioration of mental illnesses, such as memory disorder, depressive disorder, generalized anxiety disorder, bipolar disorder, and the like, as well as Parkinson's disease, or can be used as a very effective composition for the improvement of memory or cognitive function. Moreover, the strain exhibits anti-inflammatory efficacy of upregulating the expression of IL-10 (interleukin-10) and inhibiting the generation of nitric oxide (NO) and is not resistant to antibiotics, and can thus be readily applied to a variety of foods having health improvement effects.

公开(公告)号：US11447741B2

公开(公告)日：2022-09-20

申请号：US17051007

申请日：2019-06-10

Applicant: ATOGEN CO., LTD

Inventor： Bo Ram Beck ,  Ji Hee Kang ,  Gun Seok Park ,  Sung Hoon Im ,  Do Yeun Jeong ,  Yong Hyun Lee

IPC: A61K35/747 ,  A61K35/74 ,  A61K35/00 ,  C12N1/20 ,  A61P15/02 ,  C12R1/25

Abstract: A novel Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 and a composition for the prevention or treatment of vaginitis containing the same are proposed. The Lactobacillus plantarum strain ATG-K2, ATG-K6 or ATG-K8 has excellent antimicrobial effects against various pathogenic strains as well as Candida albicans and Gardnerella vaginalis, which are vaginitis pathogens, and thus can be easily used as a composition for the treatment of bacterial vaginosis, vaginal candidiasis, etc., or as a functional health food for the prevention or amelioration of these diseases.