公开(公告)号：US12128027B2

公开(公告)日：2024-10-29

申请号：US18120033

申请日：2023-03-10

Applicant: ATAI Therapeutics, Inc.

Inventor： Srinivas G. Rao ,  Glen Short ,  Majed Fawaz ,  Prerak Patel ,  Santnu Patel

IPC: A61K31/4045 ,  A61K9/00 ,  A61K9/70 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  A61K47/42

CPC classification number: A61K31/4045 ,  A61K9/006 ,  A61K9/7007 ,  A61K47/10 ,  A61K47/12 ,  A61K47/26 ,  A61K47/32 ,  A61K47/38 ,  A61K47/42

Abstract: Pharmaceutical compositions including an amorphous N—N-dimethyltryptamine (DMT) or a pharmaceutically acceptable salt or prodrug thereof, and a polymeric carrier are described. These compositions are suitable for buccal or sublingual administration to a patient. Methods of treating disorders, including neurological disorders, by administration of these compositions are described.