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公开(公告)号：US20240277719A1
公开(公告)日：2024-08-22
申请号：US18570673
申请日：2022-06-17
IPC分类号： A61K31/5375 , A61K9/00 , A61K31/216 , A61K31/496 , A61K31/5377 , A61P11/04
CPC分类号： A61K31/5375 , A61K9/0053 , A61K31/216 , A61K31/496 , A61K31/5377 , A61P11/04
摘要： Methods of treating sleep apnea and snoring comprising administering a norepinephrine reuptake inhibitor, optionally in the absence of an antimuscarinic agent, and optionally as a monotherapy, are described herein. Pharmaceutical compositions comprising norepinephrine reuptake inhibitors, such as edivoxetine and viloxazine, are also described.
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公开(公告)号：US20240358709A1
公开(公告)日：2024-10-31
申请号：US18687660
申请日：2022-08-30
IPC分类号： A61K31/5375 , A61F5/56 , A61K31/138 , A61K31/216 , A61K31/437 , A61K31/496 , A61P11/04
CPC分类号： A61K31/5375 , A61F5/566 , A61K31/138 , A61K31/216 , A61K31/437 , A61K31/496 , A61P11/04
摘要： Methods of treating pharyngeal airway collapse (e.g., sleep apnea) by administering a norepinephrine reuptake inhibitor (NRI) in combination with mandibular advancement device (MAD) therapy are described herein. The treatment may further comprise administration of a muscarinic receptor antagonist (MRA) and/or a hypnotic.
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3.发明公开公开(公告)号：US20240189328A1
公开(公告)日：2024-06-13
申请号：US18286399
申请日：2022-04-15
IPC分类号： A61K31/00 , A61K31/138 , A61K31/216 , A61K31/433 , A61K31/5375 , A61P11/04
CPC分类号： A61K31/658 , A61K31/138 , A61K31/216 , A61K31/433 , A61K31/5375 , A61P11/04
摘要： Pharmaceutical compositions comprising a norepinephrine reuptake inhibitor (NRI) and a cannabinoid and optionally a muscarinic receptor antagonist (MRA) and/or carbonic anhydrase inhibitor (CAI) and methods of treating sleep apnea are described herein.
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