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公开(公告)号:US20250027052A1
公开(公告)日:2025-01-23
申请号:US18778486
申请日:2024-07-19
Applicant: AMGEN INC.
Inventor: Eugenia ZAH , Natalia GOMEZ , Kristine DARIS , Xing MA
Abstract: Dual vector systems, and mammalian host cells comprising them, for the expression of multi chain molecules are provided where each vector employs a different promoter driving the expression of a selectable marker. The mammalian host cells can be used for producing a recombinant protein of interest in a mammalian cell culture.