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公开(公告)号:US20220340911A1
公开(公告)日:2022-10-27
申请号:US17634708
申请日:2020-08-13
Applicant: AMGEN INC.
Inventor: Wei GU , Essa Hu HARRINGTON , Oliver HOMANN
IPC: C12N15/113 , C12N15/10 , A61K47/00
Abstract: The present invention relates to RNAi constructs for reducing expression of the SLC30A8 gene. Methods of using such RNAi constructs to treat or prevent disease, such as pre-diabetes or diabetes are also described.