公开(公告)号：US20240194301A1

公开(公告)日：2024-06-13

申请号：US18286242

申请日：2022-05-18

Applicant: AMGEN INC.

Inventor： Nicholas DeSantis ,  Shaun Devitt

IPC: G16C20/10 ,  C12Q1/22

CPC classification number: G16C20/10 ,  C12Q1/22

Abstract: Systems and methods are provided for evaluate inactivation kinetics of a biological indicator using a resistometer that is intended for a gaseous sterilization process. The gaseous sterilization process may include multiple sterilant gas injection phases. Systems and methods are provided for evaluating correlation of D values, obtained by both enumeration and fraction negative methods for determining viable spore counts, and to determine whether there are any serious deviations from a linear survivor curve that is based on the enumeration and fraction negative methods.