公开(公告)号：US20220378908A1

公开(公告)日：2022-12-01

申请号：US17771313

申请日：2020-10-23

Applicant: AMGEN INC.

Inventor： Chen Zhu ,  Daniel Gerard Greene ,  Qi Hao ,  Sekhar Kanapuram ,  Michael J. Treuheit

IPC: A61K39/395 ,  A61K47/26 ,  A61K47/10 ,  A61J1/14 ,  A61J1/10

Abstract: The present invention relates to compositions and methods for minimizing protein loss (e.g., due to adsorption to solid surfaces) at low protein concentrations. Inventions disclosed herein generally relate to the field of compositions comprising proteins, in particular, pharmaceutical compositions comprising therapeutic proteins at low protein concentrations. Inventions disclosed herein also relate to methods of administering the composition to a subject in need thereof.