公开(公告)号：US20170252363A1

公开(公告)日：2017-09-07

申请号：US15447056

申请日：2017-03-01

Applicant: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

Inventor： Seon-Yong JEONG ,  Si Young YANG ,  Eun Kuk PARK ,  Jeong Hyun KIM ,  Mun-Chang KIM

IPC: A61K31/7048 ,  A23L33/10

CPC classification number: A61K31/7048 ,  A23L33/10 ,  A23V2002/00

Abstract: Provided is a pharmaceutical composition for preventing, improving, or treating postmenopausal osteoporosis in women, the composition including, as an active ingredient, scopolin, a derivative thereof, or a pharmaceutically acceptable salt thereof, wherein scopolin has good efficacy in stimulating osteoblast differentiation, and is also effective in inhibiting a reduction in bone density after menopause, low density in a bone microstructure, a reduction in a bone formation marker in the blood, and an increase in a bone resorption marker. Therefore, scopolin and the composition including the same as an active ingredient are expected to be useful as pharmaceutical preparations for the prevention, improvement, or treatment of postmenopausal osteoporosis in women.