公开(公告)号：US11510911B2

公开(公告)日：2022-11-29

申请号：US16495555

申请日：2018-03-20

Applicant: AJOU UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION

Inventor： Hyun Goo Woo ,  Sarah Yoon ,  Eun-Ju Lee

IPC: A61K31/44 ,  A61K39/395 ,  C12N15/113 ,  A61K45/06 ,  C12Q1/6886 ,  G01N33/574

Abstract: The present invention relates to a method for predicting susceptibility to sorafenib treatment by using an SULF2 gene, and a composition for treatment of sorafenib-resistant cancer using the SULF2 expression inhibition. The method for predicting susceptibility to sorafenib treatment by using the SULF2 gene according to the present invention can enable achievement of an optimal therapeutic effect by administering a drug suitable for cancer patients, and the composition for treatment of sorafenib-resistant cancer using the SULF2 inhibition has a very excellent anticancer treatment effect.