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公开(公告)号：US20180291403A1
公开(公告)日：2018-10-11
申请号：US15927622
申请日：2018-03-21
Applicant: AJINOMOTO CO., INC.
Inventor： Yasushi Hoshino , Akiko Matsudaira , Mika Moriya , Nobuhisa Nitta , Yosuke Nishio
Abstract: The present invention describes an efficient method for producing linalool. The present invention provides a method for producing linalool, the method including culturing a microorganism expressing linalool synthase in a culture medium to produce linalool. The present invention also describes a microorganism able to express linalool synthase and efficiently produce linalool.
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公开(公告)号：US10941420B2
公开(公告)日：2021-03-09
申请号：US15927573
申请日：2018-03-21
Applicant: AJINOMOTO CO., INC.
Inventor： Yasushi Hoshino , Yoshiko Inoue , Mika Moriya , Akiko Matsudaira , Yosuke Nishio
Abstract: The present invention provides a composition containing linalool, wherein the composition contains a high amount of either enantiomer R-linalool or S-linalool, and has a high content rate of linalool. The present invention also provides a production method for producing the composition. The present invention further provides a composition containing volatile components including linalool, in which a content of linalool in a total content of the volatile components in the composition is 60% or more, and the linalool is present as R-linalool or S-linalool in an amount of 50% or more of the enantiomer, and a production method therefor.
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Patent Agency Ranking
公开(公告)号：US20130260425A1
公开(公告)日：2013-10-03
申请号：US13912313
申请日：2013-06-07
Applicant: Ajinomoto Co., Inc.
Inventor： Hidetaka Doi , Yasushi Hoshino , Yuri Masumitsu , Yoshihiro Usuda
CPC classification number: C12P13/08 , C07K14/245 , C12N1/20 , C12N1/38 , C12N15/746 , C12P13/04
Abstract: A method for producing an L-amino acid includes culturing a bacterium which belongs to the family Enterobacteriaceae and has an L-amino acid-producing ability in a medium containing a carbon source selected from a fatty acid and an alcohol, and collecting the L-amino acid from the medium. A bacterium which has been subjected to a modification including at least one of enhancement of oxyS gene expression, enhancement of fixABC gene expression, and combination thereof, is used as the bacterium, or a substance that reduces intracellular hydrogen peroxide concentration of the bacterium is added to the medium.
Abstract translation: L-氨基酸的制造方法包括在含有选自脂肪酸和醇的碳源的培养基中培养属于肠杆菌科的细菌并具有L-氨基酸生产能力的细菌， 来自培养基的氨基酸。 使用已经进行了包括oxyS基因表达增强，固定化ABC基因表达的增强及其组合中的至少一种的修饰的细菌作为细菌，或者添加减少细菌的细胞内过氧化氢浓度的物质 到中等
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公开(公告)号：US20180291402A1
公开(公告)日：2018-10-11
申请号：US15927573
申请日：2018-03-21
Applicant: AJINOMOTO CO., INC.
Inventor： Yasushi Hoshino , Yoshiko Inoue , Mika Moriya , Akiko Matsudaira , Yosuke Nishio
Abstract: The present invention provides a composition containing linalool, wherein the composition contains a high amount of either enantiomer R-linalool or S-linalool, and has a high content rate of linalool. The present invention also provides a production method for producing the composition. The present invention further provides a composition containing volatile components including linalool, in which a content of linalool in a total content of the volatile components in the composition is 60% or more, and the linalool is present as R-linalool or S-linalool in an amount of 50% or more of the enantiomer, and a production method therefor.
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公开(公告)号：US20150218605A1
公开(公告)日：2015-08-06
申请号：US14687025
申请日：2015-04-15
Applicant: AJINOMOTO CO., INC.
Inventor： Yasushi Hoshino , Yukiko Miyagawa , Seizaburo Shiraga
IPC: C12P13/08
CPC classification number: C12P13/08 , C12N9/93 , C12P13/04 , C12Y602/01003
Abstract: A method for producing an L-amino acid using a fatty acid as the carbon source is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been introduced with the lcfA gene, in a medium containing a fatty acid, and collecting the L-amino acid from the medium.
Abstract translation: 提供了使用脂肪酸作为碳源生产L-氨基酸的方法。 通过在含有脂肪酸的培养基中培养属于肠杆菌科的具有L-氨基酸生产能力的细菌，其已经与lcfA基因一起引入，并且收集L-氨基酸产生L-氨基酸 酸从介质中。
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公开(公告)号：US20150211033A1
公开(公告)日：2015-07-30
申请号：US14687003
申请日：2015-04-15
Applicant: AJINOMOTO CO., INC.
Inventor： Yukiko Miyagawa , Yasushi Hoshino , Takuya Okada , Seizaburo Shiraga
IPC: C12P13/08
Abstract: A method for producing an L-amino acid using linoleic acid as the carbon source is provided. An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae and having an L-amino acid-producing ability, which has been modified so that the 2,4-dienoyl-CoA reductase activity is increased, in a medium containing linoleic acid, and collecting the L-amino acid from the medium.
Abstract translation: 提供了使用亚油酸作为碳源生产L-氨基酸的方法。 通过培养属于肠杆菌科的具有L-氨基酸生产能力的细菌来生产L-氨基酸，其在已经被修饰以使得2,4-二烯酰基-CoA还原酶活性增加的培养基中培养，所述培养基含有 亚油酸，并从培养基中收集L-氨基酸。
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公开(公告)号：US08951760B2
公开(公告)日：2015-02-10
申请号：US13912313
申请日：2013-06-07
Applicant: Ajinomoto Co., Inc.
Inventor： Hidetaka Doi , Yasushi Hoshino , Yuri Masumitsu , Yoshihiro Usuda
CPC classification number: C12P13/08 , C07K14/245 , C12N1/20 , C12N1/38 , C12N15/746 , C12P13/04
Abstract: A method for producing an L-amino acid includes culturing a bacterium which belongs to the family Enterobacteriaceae and has an L-amino acid-producing ability in a medium containing a carbon source selected from a fatty acid and an alcohol, and collecting the L-amino acid from the medium. A bacterium which has been subjected to a modification including at least one of enhancement of oxyS gene expression, enhancement of fixABC gene expression, and combination thereof, is used as the bacterium, or a substance that reduces intracellular hydrogen peroxide concentration of the bacterium is added to the medium.
Abstract translation: L-氨基酸的制造方法包括在含有选自脂肪酸和醇的碳源的培养基中培养属于肠杆菌科的细菌并具有L-氨基酸生产能力的细菌， 来自培养基的氨基酸。 使用已经进行了包括oxyS基因表达增强，固定化ABC基因表达的增强及其组合中的至少一种的修饰的细菌作为细菌，或者添加减少细菌的细胞内过氧化氢浓度的物质 到中等
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