公开(公告)号：US20130190320A1

公开(公告)日：2013-07-25

申请号：US13740182

申请日：2013-01-12

Applicant: ACEA Biosciences, Inc.

Inventor： Xiao XU ,  Xiaobo WANG ,  Long MAO ,  Li ZHAO ,  Biao XI ,  Wanhong XU ,  Wei TANG

IPC: A61K31/52 ,  A61K31/506 ,  C07D487/04 ,  A61K45/06 ,  C07D401/14 ,  C07D403/12 ,  C07D473/34 ,  C07D473/32 ,  A61K31/519

Abstract: The present disclosure provides pharmaceutical compounds, compositions and methods, especially as they are related to compositions and methods for the treatment of tumors and related diseases related to the dysregulation of kinase (such as EGFR (including HER), Alk, PDGFR, but not limited to) pathways.

Abstract translation: 本公开提供了药物化合物，组合物和方法，特别是因为它们与用于治疗肿瘤和与激酶失调相关的相关疾病（例如EGFR（包括HER），Alk，PDGFR）的组合物和方法有关，但不限于此 到）途径。