公开(公告)号：US11419931B2

公开(公告)日：2022-08-23

申请号：US17024628

申请日：2020-09-17

Applicant: 4D Pharma Research Limited

Inventor： Domenico Panzica ,  Amy Beth Holt ,  Suaad Ahmed ,  Anna Ettorre ,  Imke Elisabeth Mulder ,  Philip Cowie ,  Emma Raftis ,  Emma Elizabeth Clare Hennessy ,  Delphine Louise Claudette Laute-Caly ,  Aurélie Pascale Patricia Couturier-Maillard ,  Margaret Inkster Delday ,  Marsilio Adriani ,  Maria Christofi

IPC: A61K39/02 ,  A61K39/09 ,  A61K35/744 ,  A61K39/00 ,  A61P37/04

Abstract: The invention provides compositions comprising bacterial strains for stimulating the immune system and treating and preventing diseases.

公开(公告)号：US10987387B2

公开(公告)日：2021-04-27

申请号：US16691136

申请日：2019-11-21

Applicant: 4D Pharma Research Limited

Inventor： Imke Elisabeth Mulder ,  Emma Raftis ,  Delphine Louise Claudette Caly ,  Emma Elizabeth Clare Hennessy

IPC: A61K35/744 ,  A61P35/00 ,  A61K9/00

Abstract: The invention provides compositions comprising bacterial strains for treating and preventing cancer.

公开(公告)号：US20210393773A1

公开(公告)日：2021-12-23

申请号：US17245060

申请日：2021-04-30

Applicant: 4D Pharma Research Limited

Inventor： Emma Elizabeth Clare Hennessy ,  Suaad AHMED ,  Amy Beth HOLT ,  Philip COWIE ,  Anna ETTORRE ,  Samantha YUILLE ,  Imke Elisabeth MULDER

IPC: A61K39/39 ,  C12N1/20

Abstract: The invention provides compositions comprising bacterial strains for use as a vaccine adjuvant; for use in treating, preventing or delaying immunosenescence; or for use in enhancing a cell therapy, such as CAR-T. The invention also provides vaccine compositions comprising bacterial strains and one or more antigens.