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公开(公告)号：US20190139623A1
公开(公告)日：2019-05-09
申请号：US16240641
申请日：2019-01-04
申请人： 23andMe, Inc.
发明人： Katarzyna Bryc , Eric Yves Jean-Marc Durand , Joanna Louise Mountain , Robin Patrick Smith , Peilun Shan , Bradley Kittredge
IPC分类号： G16B10/00
摘要： Estimating parental contribution of ancestry includes: obtaining a set of ancestry assignment data associated with an individual's genotype data, at least some of the ancestry assignment data indicating that one or more segments of the individual's genotype data is deemed to be associated with a specific ancestry; determining whether in the individual's genotype data there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry; in the event that it is determined that there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry: specifying that parental contribution of the specific ancestry is made by both parents of the individual; in the event that it is determined that there is no confirmed region of overlapping ancestry assignment associated with the specific ancestry: statistically determining whether the parental contribution to the specific ancestry is made by only one parent of the individual or by both parents of the individual, the determination being based at least in part on one or more lengths of the one or more segments deemed to be associated with the specific ancestry; and outputting information pertaining to the parental contribution to the specific ancestry.
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公开(公告)号：US20170329915A1
公开(公告)日：2017-11-16
申请号：US15249242
申请日：2016-08-26
申请人： 23andMe, Inc.
发明人： Bradley Kittredge , Magdalene Misztal , Shirley Wu , Bertram Koelsch , Jie Wei , Pei Lun Shan , Robert John Borkowski
摘要： The disclosed inventions relate to web page templates and methods for constructing web pages, including web pages for the display of personal medical, genetic, and diagnostic information related to a physiological condition including, but not limited to, a medical condition, a trait, and a wellness condition.
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公开(公告)号：US20230142864A1
公开(公告)日：2023-05-11
申请号：US18096868
申请日：2023-01-13
申请人： 23andMe, Inc.
发明人： Katarzyna Bryc , Eric Yves Jean-Marc Durand , Joanna Louise Mountain , Robin Patrick Smith , Peilun Shan , Bradley Kittredge
摘要： Admixture generation determination includes: obtaining ancestry assignment information associated with an individual's genotype data, the ancestry assignment information at least indicating that a portion of the individual's genotype data is deemed to be associated with a specific ancestry; determining the individual's genetic ancestry summary data corresponding to the specific ancestry; estimating an admixture generation associated with the specific ancestry, the admixture generation indicating a most recent generation or a most recent generation range from which the individual has at least one non-admixed ancestor of the specific ancestry, the estimation including a maximum likelihood determination based at least in part on the individual's genetic ancestry summary data and a recombination model; and outputting the estimated admixture generation.
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公开(公告)号：US20220223233A1
公开(公告)日：2022-07-14
申请号：US17707790
申请日：2022-03-29
申请人： 23andMe, Inc.
发明人： Katarzyna Bryc , Eric Yves Jean-Marc Durand , Joanna Louise Mountain , Robin Patrick Smith , Peilun Shan , Bradley Kittredge
摘要： Estimating parental contribution of ancestry includes: obtaining a set of ancestry assignment data associated with an individual's genotype data, at least some of the ancestry assignment data indicating that one or more segments of the individual's genotype data is deemed to be associated with a specific ancestry; determining whether in the individual's genotype data there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry; in the event that it is determined that there is at least one confirmed region of overlapping ancestry assignment associated with the specific ancestry: specifying that parental contribution of the specific ancestry is made by both parents of the individual; in the event that it is determined that there is no confirmed region of overlapping ancestry assignment associated with the specific ancestry: statistically determining whether the parental contribution to the specific ancestry is made by only one parent of the individual or by both parents of the individual, the determination being based at least in part on one or more lengths of the one or more segments deemed to be associated with the specific ancestry; and outputting information pertaining to the parental contribution to the specific ancestry.
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