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公开(公告)号：US20250064839A1
公开(公告)日：2025-02-27
申请号：US18947960
申请日：2024-11-14
Applicant: STOWERS INSTITUTE FOR MEDICAL RESEARCH , THE CHILDREN'S MERCY HOSPITAL KANSAS CITY , UNIVERSITY OF KANSAS
Inventor： Linheng Li , John M. Perry , Fang Tao , Xi C. He , Anuradha Roy , Scott J. Weir , Tara Lin
IPC: A61K31/704 , A61K39/395 , A61P35/02 , C07K16/28
Abstract: The present disclosure provides, inter alia, methods for treating cancers including leukemia using low doses of an anthracycline such as doxorubicin.
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公开(公告)号：US12234329B2
公开(公告)日：2025-02-25
申请号：US17554056
申请日：2021-12-17
Applicant: University of Kansas
Inventor： Bala Subramaniam , Julian R. Silverman , Andrew M. Danby , Thomas Binder , Steffan Green
IPC: C08J3/00
Abstract: Methods of forming lignin prepolymers are provided. In an embodiment, such a method comprises adding an acid to an ozonized reaction mixture, the ozonized reaction mixture comprising ozonized lignin having a backbone, and aromatic monomers cleaved from a lignin, under conditions to react the cleaved aromatic monomers with the backbone of the ozonized lignin to form a lignin prepolymer. The methods may further comprise using the lignin prepolymer to form a lignin resin.
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公开(公告)号：US20240398895A1
公开(公告)日：2024-12-05
申请号：US18737680
申请日：2024-06-07
Applicant: University of Kansas
Inventor： Peter S. N. Rowe
Abstract: A method of treating or inhibiting a kidney disorder can include administering a therapeutically effective amount of the ASARM peptide to provide a treatment for the kidney disorder (treat disease) and/or inhibit development of the kidney disorder (prophylactic). The kidney disorder can be selected from the group consisting of chronic kidney disease mineral bone disorder (CKD-MBD), calciphylaxis, nephrogenic systemic fibrosis (NSF), end stage renal disease, and combinations thereof. The therapy can include inhibiting vascular calcification (VC), hard tissue calcification, soft tissue calcification, mineralization, or combinations thereof in the subject with the ASARM peptide. A method of inhibiting mineralization can include administering a therapeutically effective amount of the ASARM peptide to provide a treatment for inhibit mineralization in the subject. A method of treating hyperphosphatemia can include administering a therapeutically effective amount of the ASARM peptide to a subject to provide a treatment for hyperphosphatemia.
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公开(公告)号：US20240384294A1
公开(公告)日：2024-11-21
申请号：US18624863
申请日：2024-04-02
Inventor： Ziying Yan , John F. Engelhardt , Jianming Qiu , Zekun Wang
Abstract: Vectors having a nucleotide sequence having SEQ ID NO:1 or a nucleotide sequence having at least 85% identity to SEQ ID NO:1, or a portion thereof, that is capable of regulating bocaparvovirus replication, or vectors having the complement of the nucleotide sequence, and methods of using the vectors, are provided.
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公开(公告)号：US12145727B2
公开(公告)日：2024-11-19
申请号：US17891644
申请日：2022-08-19
Applicant: University of Kansas
Inventor： Ronald Martin Barrett
Abstract: Aerial vehicles, their structures and methods of locomotion are described. An aerial vehicle may include a fuselage having an x-axis, a plurality of flexible structures emanating from the fuselage that take the form of a feather, wing and/or tentacle, at least one motor, and at least one propeller driven by one or more motors. Each flexible structure may extend from a fuselage in any direction and are used to enhance the observability of the aircraft by moving and/or oscillating within a frequency band and at a magnitude that is more easily observed by and catches the human eye.
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Patent Agency Ranking
公开(公告)号：US12128012B2
公开(公告)日：2024-10-29
申请号：US17770543
申请日：2021-05-14
Applicant: University of Kansas
Inventor： Richard Barohn , John A. Stanford , Matthew Macaluso
IPC: A61K31/135 , A61P25/28
CPC classification number: A61K31/135 , A61P25/28
Abstract: A method of treating amyotrophic lateral sclerosis (ALS) is provided to extend life expectancy in a subject. The method can include administering the ketamine to a subject having ALS such that the subject has an extended life expectancy compared to life expectancy of the subject prior to being administered the ketamine. The extended life expectancy is determined by the subject having a first progression rate of ALS prior to being administered ketamine and a second progression rate of ALS after being administered ketamine. The first progression rate is faster than the second progression rate such that the progression of ALS in the subject is slowed by the ketamine.
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公开(公告)号：US20240327045A1
公开(公告)日：2024-10-03
申请号：US18681408
申请日：2022-08-05
Applicant: University of Kansas
Inventor： Ronald M. BARRETT , Mason Ross DENNELER , Zachary SCHWAB
IPC: B64U30/299 , B64U20/30 , B64U60/50
CPC classification number: B64U30/299 , B64U20/30 , B64U60/50
Abstract: This disclosure generally relates to aerial vehicles that may convert from hover-mode to missile-mode flight and back via body tilt for efficient flight and can strike wires such that neither the wires nor the aircraft are damaged, and divergence is prevented. This includes an aerial vehicle having an elongate fuselage having a nose tip, a plurality of engines connected to the fuselage, and at least three protective members connected substantially near the nose tip of the fuselage longitudinally beyond the plurality of engines.
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8.发明公开公开(公告)号：US20240298521A1
公开(公告)日：2024-09-05
申请号：US18589836
申请日：2024-02-28
Applicant: University of Kansas
Inventor： Judy Z. Wu , Maogang Gong , Bo Liu , Andrew Shultz
CPC classification number: H10K85/381 , C01B19/007 , G01J1/42 , B82Y20/00 , B82Y40/00 , C01P2002/77 , C01P2002/82 , C01P2004/04 , C01P2004/32 , C01P2004/64 , C01P2006/40
Abstract: Provided are methods of fabricating photodetectors based on heterostructures comprising graphene and mercury chalcogenide, e.g., HgTe, quantum dots. Embodiments of the methods are able to provide photodetectors that can detect MWIR light, e.g., greater than 3 mm at room temperature with responsivities R* of at least 104 A/W and detectivities D* of at least 1011 Jones. Thus, the present photodetectors outperform existing MWIR photodetectors without the need for cooling. The photodetectors themselves are also encompassed.
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公开(公告)号：US12075996B2
公开(公告)日：2024-09-03
申请号：US17085870
申请日：2020-10-30
Applicant: University of Kansas
Inventor： Stephen Clifford Waller , Alyssa Kirk Burke , Richard Kevin Gilroy , Philip Lee Johnson , James Marion Stiles , Sara Ellen Wilson
IPC: A61B17/00
CPC classification number: A61B17/0057 , A61B17/00491 , A61B2017/00292 , A61B2017/00544 , A61B2017/00641 , A61B2017/0065 , A61B2017/00876 , A61B2017/00951
Abstract: The present disclosure relates to devices and methods for delivery of a ferrofluid to a targeted treatment site, such as delivery of a ferroadhesive to a pathological fistula to occlude the fistula. A device includes a catheter having a lumen and a distal opening. A hollow solenoid is coupled to a distal section of the catheter, and a hollow core of the solenoid allows passage of a ferrofluid through the catheter and through the hollow core so that it may exit past the distal end of the hollow solenoid. The solenoid may be selectively actuated to maintain or control the position of the delivered ferrofluid.
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公开(公告)号：US12070319B2
公开(公告)日：2024-08-27
申请号：US17281121
申请日：2019-10-01
Applicant: University of Kansas
Inventor： Jennifer Villwock , Kevin Sykes
IPC: A61B5/00
CPC classification number: A61B5/4011 , A61B2560/0487
Abstract: Disclosed herein are olfactory diagnostic kits and methods for screening for an olfactory dysfunction. Also disclosed are olfactory training kits and methods for treating an olfactory dysfunction in a subject. Also disclosed is a method for diagnosing a subject for an olfactory dysfunction. Also disclosed is a method for training a subject with an olfactory dysfunction.
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