公开(公告)号：US08846746B2

公开(公告)日：2014-09-30

申请号：US13599665

申请日：2012-08-30

Applicant: Tomoya Miura ,  Yosuke Ogoshi ,  Kazuhito Ueyama ,  Dai Motoda ,  Toshihiko Iwayama ,  Koichi Suzawa ,  Hironobu Nagamori ,  Hiroshi Ueno ,  Akihiko Takahashi ,  Kazuyuki Sugimoto

Inventor： Tomoya Miura ,  Yosuke Ogoshi ,  Kazuhito Ueyama ,  Dai Motoda ,  Toshihiko Iwayama ,  Koichi Suzawa ,  Hironobu Nagamori ,  Hiroshi Ueno ,  Akihiko Takahashi ,  Kazuyuki Sugimoto

IPC: A01N43/56 ,  A61K31/415 ,  C07D405/14 ,  C07D403/14 ,  C07D403/12 ,  C07D409/12 ,  C07D401/12 ,  C07D413/12 ,  C07D405/12

CPC classification number: C07D403/12 ,  C07D401/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D413/12

Abstract: The present invention provides a pyrazole compound of the following general Formula [Ib] having SGLT1 inhibitory activity, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, and its pharmaceutical use: wherein each symbol is the same as defined in the description.

Abstract translation: 本发明提供具有SGLT1抑制活性的以下通式[Ib]的吡唑化合物或其药学上可接受的盐，包含其的药物组合物及其药物用途：其中每个符号与描述中定义的相同 。

公开(公告)号：US20130085132A1

公开(公告)日：2013-04-04

申请号：US13599665

申请日：2012-08-30

Applicant: Tomoya MIURA ,  Yosuke OGOSHI ,  Kazuhito UEYAMA ,  Dai MOTODA ,  Toshihiko IWAYAMA ,  Koichi SUZAWA ,  Hironobu NAGAMORI ,  Hiroshi UENO ,  Akihiko TAKAHASHI ,  Kazuyuki SUGIMOTO

Inventor： Tomoya MIURA ,  Yosuke OGOSHI ,  Kazuhito UEYAMA ,  Dai MOTODA ,  Toshihiko IWAYAMA ,  Koichi SUZAWA ,  Hironobu NAGAMORI ,  Hiroshi UENO ,  Akihiko TAKAHASHI ,  Kazuyuki SUGIMOTO

IPC: C07D403/12 ,  C07D405/12 ,  C07D403/14 ,  C07D413/12 ,  C07D409/12 ,  C07D401/12 ,  C07D405/14

CPC classification number: C07D403/12 ,  C07D401/12 ,  C07D403/14 ,  C07D405/12 ,  C07D405/14 ,  C07D409/12 ,  C07D413/12

Abstract: The present invention provides a pyrazole compound of the following general Formula [Ib] having SGLT1 inhibitory activity, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the same, and its pharmaceutical use: wherein each symbol is the same as defined in the description.