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公开(公告)号:US20090018438A1
公开(公告)日:2009-01-15
申请号:US11775915
申请日:2007-07-11
申请人: Tobias Schroder , Marcos F. Vidal Melo , Guido Musch , Robert Scott Harris , Jose G. Venegas , Tilo Winkler
发明人: Tobias Schroder , Marcos F. Vidal Melo , Guido Musch , Robert Scott Harris , Jose G. Venegas , Tilo Winkler
IPC分类号: A61B6/00
摘要: An input function indicative of a time-activity curve in pulmonary arterial plasma is produced from a series of PET image frames in lieu of manual blood sampling. Two manually acquired blood samples are input along with pixel values of a blood pool region of interest (ROI) in the PET image frames into a two-parameter model of the ROI's time-activity curve. In an iterative process the model converges to accurately indicate the amount of 18F-FDG tracer in the arterial blood. Pulmonary uptake of the tracer is assessed with the PET image frames and the calculated input function.
摘要翻译: 一系列PET图像帧代替手动血液取样产生指示肺动脉血浆中的时间 - 活动曲线的输入函数。 将两个手动获取的血液样本与PET图像帧中的感兴趣的血池区域(ROI)的像素值一起输入到ROI的时间 - 活动曲线的双参数模型中。 在迭代过程中,模型收敛以精确指示动脉血中18F-FDG示踪剂的量。 使用PET图像帧和计算的输入函数评估示踪剂的肺部摄取。
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公开(公告)号:US08527034B2
公开(公告)日:2013-09-03
申请号:US11775915
申请日:2007-07-11
申请人: Tobias Schroder , Marcos F. Vidal Melo , Guido Musch , Robert Scott Harris , Jose G. Venegas , Tilo Winkler
发明人: Tobias Schroder , Marcos F. Vidal Melo , Guido Musch , Robert Scott Harris , Jose G. Venegas , Tilo Winkler
IPC分类号: A61B6/00
摘要: An input function indicative of a time-activity curve in pulmonary arterial plasma is produced from a series of PET image frames in lieu of manual blood sampling. Two manually acquired blood samples are input along with pixel values of a blood pool region of interest (ROI) in the PET image frames into a two-parameter model of the ROI's time-activity curve. In an iterative process the model converges to accurately indicate the amount of 18F-FDG tracer in the arterial blood. Pulmonary uptake of the tracer is assessed with the PET image frames and the calculated input function.
摘要翻译: 一系列PET图像帧代替手动血液取样产生指示肺动脉血浆中的时间 - 活动曲线的输入函数。 将两个手动获取的血液样本与PET图像帧中的感兴趣的血池区域(ROI)的像素值一起输入到ROI的时间 - 活动曲线的双参数模型中。 在迭代过程中,模型收敛以精确指示动脉血中18F-FDG示踪剂的量。 使用PET图像帧和计算的输入函数评估示踪剂的肺部摄取。
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