Measuring Tissue Shear Wave Properties using One Excitation Pulse and Excitation Pulses having Different Widths and Shapes

    公开(公告)号:US20170367683A1

    公开(公告)日:2017-12-28

    申请号:US15090357

    申请日:2016-04-04

    IPC分类号: A61B8/08 G01S7/52 G01S7/62

    摘要: Methods and apparatus measuring tissue nonlinear shear wave property are disclosed. When tissue shear responses are different to ultrasound radiation forces generated by pulses having different shapes, its nonlinear effect can be used to estimate tissue property at single location without measurements of group velocities or phase velocities. Ultrasound radiation force using a single tone burst pulse is applied to a selected location in a tissue region. The induced shear wave is detected in the region and its spectral distribution is calculated and analyzed. This detection may be repeated with other excitation pulses having different widths or different shapes at the same location. The spectral analysis of the detected shear wave is performed according to a nonlinear shear model for solving nonlinearity and viscoelasticity of the tissue at a single location in a tissue region. The detection location can be at one point at a time for imaging two-dimensional or three-dimensional tissue nonlinearities and shear wave properties. The property includes nonlinear magnitude variations, nonlinear phase variations, nonlinear coefficients, and viscoelasticity. The induced shear wave are detected at multiple locations along the shear propagation directions in the tissue region for calculating different shear group velocities and different shear phase velocities using different excitation pulses, and calculating nonlinearity and viscoelasticity. A difference between certain aspects of this disclosure and the prior art of ultrasound elastography is the utilization of nonlinear responses of the tissue shear property.

    Lewis and bronsted-lowry acid-catalyzed production 5-hydroxymethylfurfural (HMF) from glucose
    2.
    发明授权
    Lewis and bronsted-lowry acid-catalyzed production 5-hydroxymethylfurfural (HMF) from glucose 有权
    路易斯和青铜酸催化从葡萄糖生产5-羟甲基糠醛(HMF)

    公开(公告)号:US08642791B2

    公开(公告)日:2014-02-04

    申请号:US13313389

    申请日:2011-12-07

    IPC分类号: C07D307/46

    CPC分类号: C07D307/48

    摘要: Described is a process to make hydroxymethylfurfural (HMF) from glucose. The process includes the steps of reacting a feedstock solution comprising glucose, in the presence of a homogeneous Brønsted acid catalyst and a homogeneous Lewis acid catalyst, in a reaction vessel containing a biphasic reaction medium. The reaction medium includes an aqueous reaction solution and a substantially immiscible organic extraction solution. HMF is produced in the aqueous reaction solution and extracted into the organic extraction solution.

    摘要翻译: 描述了从葡萄糖制备羟甲基糠醛(HMF)的方法。 该方法包括在含有双相反应介质的反应容器中使包含葡萄糖的原料溶液在均相布朗斯台德酸催化剂和均相路易斯酸催化剂存在下反应的步骤。 反应介质包括水性反应溶液和基本上不混溶的有机萃取溶液。 在反应溶液中生成HMF,并萃取到有机萃取溶液中。

    LEWIS AND BRONSTED-LOWRY ACID-CATALYZED PRODUCTION OF 5-HYDROXYMETHYLFURFURAL (HMF) FROM GLUCOSE
    3.
    发明申请
    LEWIS AND BRONSTED-LOWRY ACID-CATALYZED PRODUCTION OF 5-HYDROXYMETHYLFURFURAL (HMF) FROM GLUCOSE 有权
    来自葡萄糖的五羟基甲基纤维素(HMF)的低温和低温酸催化生产

    公开(公告)号:US20130150595A1

    公开(公告)日:2013-06-13

    申请号:US13313389

    申请日:2011-12-07

    IPC分类号: C07D307/68

    CPC分类号: C07D307/48

    摘要: Described is a process to make hydroxymethylfurfural (HMF) from glucose. The process includes the steps of reacting a feedstock solution comprising glucose, in the presence of a homogeneous Brønsted acid catalyst and a homogeneous Lewis acid catalyst, in a reaction vessel containing a biphasic reaction medium. The reaction medium includes an aqueous reaction solution and a substantially immiscible organic extraction solution. HMF is produced in the aqueous reaction solution and extracted into the organic extraction solution.

    摘要翻译: 描述了从葡萄糖制备羟甲基糠醛(HMF)的方法。 该方法包括在含有双相反应介质的反应容器中使包含葡萄糖的原料溶液在均相布朗斯台德酸催化剂和均相路易斯酸催化剂存在下反应的步骤。 反应介质包括水性反应溶液和基本上不混溶的有机萃取溶液。 在反应溶液中生成HMF,并萃取到有机萃取溶液中。

    Measuring tissue shear wave properties using one excitation pulse and excitation pulses having different widths and shapes

    公开(公告)号:US10327739B2

    公开(公告)日:2019-06-25

    申请号:US15090357

    申请日:2016-04-04

    IPC分类号: A61B8/08 G01S7/52 G01S7/62

    摘要: Ultrasound radiation using a single tone burst pulse is applied to a selected location in a tissue region. The induced shear wave is detected in the region and its spectral distribution is calculated and analyzed. This detection may be repeated with other excitation pulses having different widths or different shapes at the same location. The spectral analysis of the detected shear wave is performed according to a nonlinear shear model for solving nonlinearity and viscoelasticity of the tissue at a single location. The detection location can be at one point at a time for imaging two-dimensional or three-dimensional tissue nonlinearities and shear wave properties including nonlinear magnitude variations, nonlinear phase variations, nonlinear coefficients, and viscoelasticity. The induced shear wave are detected at multiple locations along the shear propagation directions for calculating different shear group velocities and different shear phase velocities using different excitation pulses, and calculating nonlinearity and viscoelasticity.