公开(公告)号：US10195350B2

公开(公告)日：2019-02-05

申请号：US13600060

申请日：2012-08-30

申请人： Martin J. Gibler ,  Mark A. Bennett ,  Kenneth R. Waeber ,  Kenneth E. Hogue ,  Christoph L. Gillum ,  Patrick A. Harrell ,  David A. Parrott ,  Sean E. Mackey ,  Rajkumar V. Conjeevaram ,  Thomas Rebne ,  Bradley A. Clark ,  Jeremy L. Hemingway ,  Ji Zhou

发明人： Martin J. Gibler ,  Mark A. Bennett ,  Kenneth R. Waeber ,  Kenneth E. Hogue ,  Christoph L. Gillum ,  Patrick A. Harrell ,  David A. Parrott ,  Sean E. Mackey ,  Rajkumar V. Conjeevaram ,  Thomas Rebne ,  Bradley A. Clark ,  Jeremy L. Hemingway ,  Ji Zhou

IPC分类号： A61M5/315 ,  A61M5/145 ,  B65B1/04 ,  A61M5/31

摘要： A syringe containing a high water content product and for use in a drug infusion system is provided. The syringe includes a plunger carrying front and rear o-rings made of a diene rubber compound such as chlorobutyl rubber or bromobutyl rubber to impart very low gas permeability characteristics to the o-rings. The plunger may be molded as a single part or in two parts. If molded as one part with radially-engaging mold portions, the seal glands in the plunger may include parting lines from the mold. If molded as two parts with axially-engaging mold portions, the front seal gland may include a sealing surface and under cut that has no parting line. The o-rings may be surface treated with a lubricant to improve sealing where the molding process gives rise to parting lines in the seal glands.

公开(公告)号：US20130102994A1

公开(公告)日：2013-04-25

申请号：US13600060

申请日：2012-08-30

申请人： Martin J. Gibler ,  Mark A. Bennett ,  Kenneth R. Waeber ,  Kenneth E. Hogue ,  Christoph L. Gillum ,  Patrick A. Harrell ,  David A. Parrott ,  Sean E. Mackey ,  Rajkumar V. Conjeevaram ,  Thomas Rebne ,  Bradley A. Clark ,  Jeremy L. Hemingway ,  Ji Zhou ,  Bryan L. Wiesner

发明人： Martin J. Gibler ,  Mark A. Bennett ,  Kenneth R. Waeber ,  Kenneth E. Hogue ,  Christoph L. Gillum ,  Patrick A. Harrell ,  David A. Parrott ,  Sean E. Mackey ,  Rajkumar V. Conjeevaram ,  Thomas Rebne ,  Bradley A. Clark ,  Jeremy L. Hemingway ,  Ji Zhou ,  Bryan L. Wiesner

IPC分类号： A61M5/315 ,  B65B1/04

CPC分类号： A61M5/31505 ,  A61M5/1452 ,  A61M5/315 ,  A61M5/31513 ,  A61M2005/3117 ,  A61M2205/0222 ,  B65B1/04

摘要： A syringe containing a high water content product and for use in a drug infusion system is provided. The syringe includes a plunger carrying front and rear o-rings made of a diene rubber compound such as chlorobutyl rubber or bromobutyl rubber to impart very low gas permeability characteristics to the o-rings. The plunger may be molded as a single part or in two parts. If molded as one part with radially-engaging mold portions, the seal glands in the plunger may include parting lines from the mold. If molded as two parts with axially-engaging mold portions, the front seal gland may include a sealing surface and under cut that has no parting line. The o-rings may be surface treated with a lubricant to improve sealing where the molding process gives rise to parting lines in the seal glands.

摘要翻译： 提供含有高含水量产品并用于药物输注系统的注射器。 注射器包括承载由二烯橡胶化合物如氯丁基橡胶或溴丁基橡胶制成的前O形环和后O形环的柱塞，以向O形环赋予非常低的气体渗透性。 柱塞可以模制为单个部件或两部分。 如果模制成具有径向接合的模具部分的一部分，则柱塞中的密封压盖可以包括来自模具的分型线。 如果模制成具有轴向接合的模具部分的两个部件，则前密封压盖可以包括没有分型线的密封表面和下切口。 O型圈可以用润滑剂进行表面处理，以改善密封，其中成型工艺在密封压盖中产生分型线。