公开(公告)号：US09848601B2

公开(公告)日：2017-12-26

申请号：US12935289

申请日：2009-04-10

申请人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Mitsugu Iwasa

发明人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Mitsugu Iwasa

IPC分类号： A01N43/40 ,  A01N43/80

CPC分类号： A01N43/40 ,  A01N43/80 ,  A01N25/30 ,  A01N2300/00

摘要： To provide a pesticidal composition having a stable and high pesticidal effect. The pesticidal composition comprises a pyridine compound represented by the formula (I): (wherein R1 is CH2CN or and each of R2 and R3 which are independent of each other, is a hydrogen atom, a halogen atom, C1-6 alkyl or C1-6 alkoxy) or its salt and at least one potency-enhancing component selected from the group consisting of a nonionic surface active agent, an anionic surface active agent, a cationic surface active agent, an amphoteric surface active agent, an animal or plant oil, a mineral oil, a water-soluble polymer, a resin and a wax.

公开(公告)号：US5168113A

公开(公告)日：1992-12-01

申请号：US471337

申请日：1990-01-29

申请人： Takahiro Haga ,  Yasuhiro Tsujii ,  Tatsuo Isogai ,  Shigeo Murai ,  Hisayoshi Jonishi ,  Tokiya Kimura ,  Hiroshi Sasaki ,  Takao Awazu ,  Toshihiro Tanaka

发明人： Takahiro Haga ,  Yasuhiro Tsujii ,  Tatsuo Isogai ,  Shigeo Murai ,  Hisayoshi Jonishi ,  Tokiya Kimura ,  Hiroshi Sasaki ,  Takao Awazu ,  Toshihiro Tanaka

IPC分类号： A01N43/40 ,  C07D213/82 ,  C07D213/89 ,  C07D401/12

CPC分类号： C07D213/82 ,  A01N43/40 ,  C07D213/89 ,  C07D401/12

摘要： A mercapto-substituted pyridine compound having formula (I): ##STR1## where R.sub.1 and R.sub.2 are alkyl groups, and n is 0 or 1, and salts thereof and a process for preparing the same are disclosed. The mercapto-substituted pyridine compound is useful as an intermediate for preparing a herbicidal compound.The present invention further provides aminocarbonyl-substituted pyridinesulfinic acid (ACPS) or salts thereof as the precursor of aminosulfonyl-substituted pyridinecarbonic acid amide compound (APCA) which is useful as the starting material for agricultural chemicals, medicine, etc. Moreover, the preparation process of the present invention is an industrially advantageous preparation process which is capable of preparing in a series of steps from mercapto-substituted pyridinecarboxylic acid amide compound (MPCA) or aminocarbonyl-substituted halogenopyridine compound (ACHP) to ACPS or salts thereof, and further to APCA.

摘要翻译： 公开了具有式（I）的巯基取代的吡啶化合物：其中R 1和R 2是烷基，n是0或1，及其盐及其制备方法。 巯基取代的吡啶化合物可用作制备除草化合物的中间体。 本发明还提供氨基羰基取代的吡啶亚磺酸（ACPS）或其盐作为氨基磺酰基取代的吡啶碳酰胺化合物（APCA）的前体，其可用作农药，药物等的原料。此外，制备方法 本发明是一种工业上有利的制备方法，其能够从巯基取代的吡啶羧酸酰胺化合物（MPCA）或氨基羰基取代的卤代吡啶化合物（ACHP）到ACPS或其盐，以及APCA 。

公开(公告)号：US5128474A

公开(公告)日：1992-07-07

申请号：US558545

申请日：1990-07-27

申请人： Takahiro Haga ,  Yasuhiro Tsujii ,  Tatsuo Isogai ,  Shigeo Murai ,  Hisayoshi Jonishi ,  Tokiya Kimura ,  Hiroshi Sasaki ,  Takao Awazu ,  Toshihiro Tanaka

发明人： Takahiro Haga ,  Yasuhiro Tsujii ,  Tatsuo Isogai ,  Shigeo Murai ,  Hisayoshi Jonishi ,  Tokiya Kimura ,  Hiroshi Sasaki ,  Takao Awazu ,  Toshihiro Tanaka

IPC分类号： A01N43/40 ,  C07D213/82 ,  C07D213/89 ,  C07D401/12

CPC分类号： C07D213/82 ,  A01N43/40 ,  C07D213/89 ,  C07D401/12

摘要： An aminocarbonyl-substituted pyridinesulfinic acid intermediate for production of an herbicide having formula (V): ##STR1## wherein R.sub.3 and R.sub.4 are selected from the group consisting of hydrogen and alkyl groups, or a salt thereof. The aminocarbonyl-substituted pyridinesulfinic acid or salt thereof is useful as the precursor of aminosulfonyl-substituted pyridinecarbonic acid amide, which in turn is useful as the starting material for agricultural chemicals, medicine, etc.

摘要翻译： 用于制备具有式（V）的除草剂的氨基羰基取代的吡啶亚磺酸中间体：其中R 3和R 4选自氢和烷基，或其盐。 氨基羰基取代的吡啶亚磺酸或其盐可用作氨基磺酰基取代的吡啶碳酰胺的前体，其又可用作农药，药物等的起始原料。

公开(公告)号：US4762928A

公开(公告)日：1988-08-09

申请号：US943004

申请日：1986-12-18

申请人： Yasuhiro Tsujii ,  Tatsuo Isogai ,  Takao Awazu ,  Hisayoshi Jyonishi ,  Tokiya Kimura

发明人： Yasuhiro Tsujii ,  Tatsuo Isogai ,  Takao Awazu ,  Hisayoshi Jyonishi ,  Tokiya Kimura

IPC分类号： A01N43/40 ,  A01N47/36 ,  C07D213/73 ,  C07D213/74 ,  C07D213/75

CPC分类号： C07D213/73 ,  A01N43/40 ,  A01N47/36 ,  C07D213/74 ,  C07D213/75

摘要： A novel amino-trifluoromethylpyridine compound selected from the group consisting of 3-amino-5-trifluoromethylpyridine, 2-amino-4-trifluoromethylpyridine, and 2-amino-4,6-bis(trifluoromethyl)pyridine, and, a process for preparing the same by reacting a halogeno-trifluoromethylpyridine compound with ammonia at a temperature of 50.degree. to 200.degree. C. The compound is useful as an intermediate from which a compound effective in controlling various harmful organisms or an effective component compound of medicines can be easily derived.

摘要翻译： 选自3-氨基-5-三氟甲基吡啶，2-氨基-4-三氟甲基吡啶和2-氨基-4,6-双（三氟甲基）吡啶的新型氨基 - 三氟甲基吡啶化合物，以及制备 通过使卤代三氟甲基吡啶化合物与氨在50至200℃的温度下反应来进行。化合物可用作中间体，由此可以容易地得到有效控制各种有害生物或化合物的有效成分的化合物。

公开(公告)号：US08440824B2

公开(公告)日：2013-05-14

申请号：US12933980

申请日：2009-04-16

申请人： Shigeo Murai ,  Ryoji Koto ,  Hiroshi Yoshizawa ,  Takeshi Ohshima ,  Katsuyoshi Murakami ,  Takao Awazu ,  Hisayoshi Jonishi ,  Takayoshi Ando ,  Tadashi Nakamura ,  Norio Adachi ,  Akihiko Isogai

发明人： Shigeo Murai ,  Ryoji Koto ,  Hiroshi Yoshizawa ,  Takeshi Ohshima ,  Katsuyoshi Murakami ,  Takao Awazu ,  Hisayoshi Jonishi ,  Takayoshi Ando ,  Tadashi Nakamura ,  Norio Adachi ,  Akihiko Isogai

IPC分类号： C07D239/02

CPC分类号： C07D239/42 ,  C07D239/52 ,  C07D401/12

摘要： To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products.The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.

摘要翻译： 提供一种制造用作农药或药物中间体的嘧啶化合物的方法，其操作简单，产率高，仅产生少量副产物。 该方法包括使式（I）表示的化合物与式（II）表示的化合物在吡啶化合物的存在下反应，制得由式（III）表示的化合物，式（IV）表示的化合物 ）或它们的混合物。

公开(公告)号：US09629360B2

公开(公告)日：2017-04-25

申请号：US13808218

申请日：2011-07-05

申请人： Takao Awazu ,  Mitsuo Sano ,  Akira Nakagawa

发明人： Takao Awazu ,  Mitsuo Sano ,  Akira Nakagawa

IPC分类号： A01N25/30 ,  A01N25/04 ,  A01N43/40 ,  A01P7/04 ,  A01P3/00

CPC分类号： A01N25/30 ,  A01N25/04 ,  A01N43/40 ,  A01N43/88 ,  A01N43/90 ,  A01N47/18 ,  A01N51/00 ,  A01N57/16

摘要： A water-based pesticidal suspension comprises (a) flonicamid, (b) a polycarboxylate surfactant, (c) a sulfonate surfactant, and (d) water. The sulfonate surfactant (c) is at least one member selected from the group consisting of an alkyl sulfosuccinate, a lignosulfonate, a C8-18 alkyl benzene sulfonate and a C8-18 alkyl diphenyl ether disulfonate. An average particle size of the volume distribution of (a) flonicamid is preferably from 0.5 μm to 10 μm. The polycarboxylate surfactant (b) is preferably a sodium salt of maleic acid/olefin copolymer.

公开(公告)号：US20110028521A1

公开(公告)日：2011-02-03

申请号：US12935289

申请日：2009-04-10

申请人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Mitsugu Iwasa

发明人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Mitsugu Iwasa

IPC分类号： A01N43/40 ,  A01P7/00

CPC分类号： A01N43/40 ,  A01N43/80 ,  A01N25/30 ,  A01N2300/00

摘要： To provide a pesticidal composition having a stable and high pesticidal effect. The pesticidal composition comprises a pyridine compound represented by the formula (I): (wherein R1 is CH2CN or and each of R2 and R3 which are independent of each other, is a hydrogen atom, a halogen atom, C1-6 alkyl or C1-6 alkoxy) or its salt and at least one potency-enhancing component selected from the group consisting of a nonionic surface active agent, an anionic surface active agent, a cationic surface active agent, an amphoteric surface active agent, an animal or plant oil, a mineral oil, a water-soluble polymer, a resin and a wax.

摘要翻译： 提供具有稳定和高杀虫作用的杀虫剂组合物。 杀虫剂组合物包含由式（I）表示的吡啶化合物：其中R1是CH2CN，R2和R3彼此独立的是氢原子，卤素原子，C1-6烷基或C1- 6烷氧基）或其盐和至少一种选自非离子表面活性剂，阴离子表面活性剂，阳离子表面活性剂，两性表面活性剂，动物或植物油的增效组分， 矿物油，水溶性聚合物，树脂和蜡。

公开(公告)号：US4241213A

公开(公告)日：1980-12-23

申请号：US75022

申请日：1979-09-13

申请人： Ryuzo Nishiyama ,  Kanichi Fujikawa ,  Isao Yokomichi ,  Rikuo Nasu ,  Takao Awazu ,  Junichi Kawashima

发明人： Ryuzo Nishiyama ,  Kanichi Fujikawa ,  Isao Yokomichi ,  Rikuo Nasu ,  Takao Awazu ,  Junichi Kawashima

IPC分类号： C07D213/26 ,  C07D213/61 ,  C07D213/64

CPC分类号： C07D213/61

摘要： 2-Chloro-5-trichloromethyl pyridine is produced by reacting .beta.-picoline with chlorine in a gaseous phase at 300.degree. to 500.degree. C. in the presence of an inert diluent of nitrogen, a halogenated methane, a halogenated ethane a halogenated ethylene or a mixture thereof. 2-Chloro-5-trichloromethyl pyridine is useful as an intermediate for medicines, agricultural chemicals, dyes especially herbicides.

摘要翻译： 2-甲基-5-三氯甲基吡啶是在惰性稀释氮气，卤代甲烷，卤代乙烷，卤化乙烯或卤代乙烷的存在下，在300〜500℃下，使β-吡啶啉与氯气在氯气中反应生成的 它们的混合物。 2-氯-5-三氯甲基吡啶可用作药物，农药，染料，特别是除草剂的中间体。

公开(公告)号：US08529926B2

公开(公告)日：2013-09-10

申请号：US12867854

申请日：2009-03-11

申请人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Taku Hamamoto

发明人： Masayuki Morita ,  Takao Awazu ,  Akira Nakagawa ,  Taku Hamamoto

IPC分类号： A01N25/00 ,  A01N43/56

CPC分类号： A01N43/56 ,  A01N25/02 ,  A01N25/04 ,  A01N25/30 ,  A01N2300/00

摘要： To provide a formulation composition which improves the controlling effect of an anthranilamide compound against pests. A pesticide composition which is a concentrated composition containing an anthranilamide compound as a pesticidal active ingredient, a dispersant and a hydrophilic organic solvent, characterized in that when the composition is diluted with water, the anthranilamide compound precipitates as solid particles in water.

摘要翻译： 提供一种改善邻氨基苯甲酰胺化合物对害虫的控制作用的制剂组合物。 作为含有邻氨基苯甲酰胺化合物作为杀虫活性成分的浓缩组合物的农药组合物，分散剂和亲水性有机溶剂，其特征在于，当用水稀释组合物时，邻氨基苯甲酰胺化合物作为固体颗粒沉淀在水中。

公开(公告)号：US20110021774A1

公开(公告)日：2011-01-27

申请号：US12933980

申请日：2009-04-16

申请人： Shigeo Murai ,  Ryoji Koto ,  Hiroshi Yoshizawa ,  Takeshi Ohshima ,  Katsuyoshi Murakami ,  Takao Awazu ,  Hisayoshi Jonishi ,  Takayoshi Ando ,  Tadashi Nakamura ,  Norio Adachi ,  Akihiko Isogai

发明人： Shigeo Murai ,  Ryoji Koto ,  Hiroshi Yoshizawa ,  Takeshi Ohshima ,  Katsuyoshi Murakami ,  Takao Awazu ,  Hisayoshi Jonishi ,  Takayoshi Ando ,  Tadashi Nakamura ,  Norio Adachi ,  Akihiko Isogai

IPC分类号： C07D401/12 ,  C07D239/42

CPC分类号： C07D239/42 ,  C07D239/52 ,  C07D401/12

摘要： To provide a method for producing pyrimidine compound useful as an intermediate for agricultural chemicals or pharmaceuticals, which is simple in operation, presents high yield and produces only a small amount of by-products.The method comprises reacting a compound represented by the formula (I) with a compound represented by the formula (II) in the presence of a pyridine compound to produce a compound represented by the formula (III), a compound represented by the formula (IV) or their mixture.

摘要翻译： 提供一种制造用作农药或药物中间体的嘧啶化合物的方法，其操作简单，产率高，仅产生少量副产物。 该方法包括使式（I）表示的化合物与式（II）表示的化合物在吡啶化合物的存在下反应，制得由式（III）表示的化合物，式（IV）表示的化合物 ）或它们的混合物。