公开(公告)号：US20220370189A1

公开(公告)日：2022-11-24

申请号：US17764055

申请日：2020-09-03

Applicant: WONKWANG UNIVERSITY CENTER FOR INDUSTRY-ACADEMY COOPERATION ,  POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION ,  THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY- ACADEMI COOPERATION FOUNDATION

Inventor： Seung Jae LEE ,  Jin Ah JANG ,  Young Sam CHO ,  Kyoung Duck SEO ,  Hun Jin JEONG ,  Hyo Ryung NAM ,  Ji Hyun KIM ,  Jae Hee CHUNG ,  Yeong Gwon JO ,  Dong Woo CHO ,  Dong Heon HA

IPC: A61F2/04 ,  A61L27/56 ,  A61L27/38

Abstract: Disclosed are an artificial esophageal structure having a multi-layer structure using three-dimensional bio-printing, and a manufacturing device and manufacturing method therefor. The artificial esophageal structure having a multi-layer structure according to one embodiment of the present invention comprises: a first layer in the shape of a hollow column and having a circular cross section; a second layer which is disposed inside the first layer and which is a column structure that simulates the mucosal layer of the esophagus; and an interlayer support part which is disposed between the first layer and the second layer and which maintains a gap between the layers, wherein the first layer and second layer each comprise: a plurality of column parts disposed at predetermined intervals; and a plurality of strands formed between the plurality of column parts by a dragging technique, and may have a porous structure due to pores between the plurality of strands.