公开(公告)号：US20220056051A1

公开(公告)日：2022-02-24

申请号：US17312480

申请日：2019-12-13

申请人： Abdelghani Abe ACHAB ,  Matthew L. CHILDERS ,  Jared N. CUMMING ,  Symon GATHIAKA ,  Charles A. LESBURG ,  Derun LI ,  Min LU ,  Matthew J. MITCHELTREE ,  Anandan PALANI ,  Rachel L. PALTE ,  Hongjun ZHANG ,  Merck Sharp & Dohme Corp.

发明人： Abdelghani Abe Achab ,  Matthew L. Childers ,  Jared N. Cumming ,  Symon Gathiaka ,  Charles A. Lesburg ,  Derun Li ,  Min Lu ,  Matthew J. Mitcheltree ,  Anandan Palani ,  Rachel L. Palte ,  Hongjun Zhang

IPC分类号： C07F5/02

摘要： Described herein are compounds of Formula (I), or a pharmaceutically acceptable salt thereof. The compounds of Formula (I) act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.