Method and system for sensitivity analysis in modeling blood flow characteristics
    1.
    发明授权
    Method and system for sensitivity analysis in modeling blood flow characteristics 有权
    血流特征建模灵敏度分析方法与系统

    公开(公告)号:US09424395B2

    公开(公告)日:2016-08-23

    申请号:US13864996

    申请日:2013-04-17

    摘要: Methods for determining cardiovascular information for a patient include receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of the patient's vasculature based on the patient-specific data; and creating a computational model of a blood flow characteristic based on the anatomic model. The method also includes identifying one or more of an uncertain parameter, an uncertain clinical variable, and an uncertain geometry; modifying a probability model based on one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry; determining a blood flow characteristic within the patient's vasculature based on the anatomic model and the computational model; and calculating, based on the probability model and the determined blood flow characteristic, a sensitivity of the determined fractional flow reserve to one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry.

    摘要翻译: 用于确定患者的心血管信息的方法包括接收关于患者脉管系统的几何形状的患者特异性数据; 基于患者特定的数据创建代表患者脉管系统的至少一部分的解剖模型; 并基于解剖模型创建血流特征的计算模型。 该方法还包括识别不确定参数,不确定临床变量和不确定几何中的一个或多个; 基于所识别的不确定参数,不确定临床变量或不确定几何中的一个或多个修改概率模型; 基于解剖模型和计算模型确定患者脉管系统内的血流特性; 并且基于所述概率模型和确定的血液流动特性,将所确定的分数流量储备的灵敏度计算到所识别的不确定参数,不确定的临床变量或不确定几何中的一个或多个。

    METHOD AND SYSTEM FOR SENSITIVITY ANALYSIS IN MODELING BLOOD FLOW CHARACTERISTICS
    2.
    发明申请
    METHOD AND SYSTEM FOR SENSITIVITY ANALYSIS IN MODELING BLOOD FLOW CHARACTERISTICS 有权
    血液流动特性建模中灵敏度分析的方法与系统

    公开(公告)号:US20140249784A1

    公开(公告)日:2014-09-04

    申请号:US13864996

    申请日:2013-04-17

    IPC分类号: G06F19/00

    摘要: Embodiments include systems and methods for determining cardiovascular information for a patient. A method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of the patient's vasculature based on the patient-specific data; and creating a computational model of a blood flow characteristic based on the anatomic model. The method also includes identifying one or more of an uncertain parameter, an uncertain clinical variable, and an uncertain geometry; modifying a probability model based on one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry; determining a blood flow characteristic within the patient's vasculature based on the anatomic model and the computational model of the blood flow characteristic of the patient's vasculature; and calculating, based on the probability model and the determined blood flow characteristic, a sensitivity of the determined fractional flow reserve to one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry.

    摘要翻译: 实施例包括用于确定患者的心血管信息的系统和方法。 一种方法包括接收关于患者脉管系统的几何形状的患者特定数据; 基于患者特定的数据创建代表患者脉管系统的至少一部分的解剖模型; 并基于解剖模型创建血流特征的计算模型。 该方法还包括识别不确定参数,不确定临床变量和不确定几何中的一个或多个; 基于所识别的不确定参数,不确定临床变量或不确定几何中的一个或多个修改概率模型; 基于解剖模型和患者脉管系统的血流特性的计算模型确定患者血管系统内的血流特性; 并且基于所述概率模型和确定的血液流动特性,将所确定的分数流量储备的灵敏度计算到所识别的不确定参数,不确定的临床变量或不确定几何中的一个或多个。