公开(公告)号：US20170035977A1

公开(公告)日：2017-02-09

申请号：US15304104

申请日：2015-04-14

申请人： Sanofi SA

发明人： Stefan Mayer

IPC分类号： A61M15/00

CPC分类号： A61M15/0065 ,  A61M15/0025 ,  A61M15/0091 ,  A61M2202/064 ,  A61M2207/00

摘要： The present disclosure relates to a sealing member for an inhaler and an assembly comprising the sealing member. The sealing member comprises a sealing lip. The assembly for an inhaler comprises a first part, a second part, and the sealing member which comprises the sealing lip, wherein the first part and the second part are assembled to permit relative rotational movement between the first part and the second part, and wherein the sealing lip sealingly engages a surface of the second part in order to provide a seal between the first part and the second part.

摘要翻译： 本公开涉及一种用于吸入器的密封构件和包括密封构件的组件。 密封构件包括密封唇。 用于吸入器的组件包括第一部分，第二部分和包括密封唇的密封构件，其中组装第一部分和第二部分以允许第一部分和第二部分之间的相对旋转运动，并且其中 密封唇密封地接合第二部分的表面，以便在第一部分和第二部分之间提供密封。

公开(公告)号：US20160184533A1

公开(公告)日：2016-06-30

申请号：US14892308

申请日：2014-04-26

申请人： SANOFI SA

发明人： Stefan MAYER

IPC分类号： A61M5/50 ,  A61M15/00 ,  A61M5/315

CPC分类号： A61M5/50 ,  A61M5/31533 ,  A61M15/0065 ,  A61M15/0066 ,  A61M15/0078 ,  A61M15/0081 ,  A61M2202/064 ,  A61M2205/273 ,  G06M1/246 ,  G06M3/02

摘要： A mechanism for a drug delivery device, having a first and a second state, including an engagement preventing member, and a blocking member having a blocking feature and an engagement element which is engagable with the blocking member. The blocking member is configured to engage with the engagement element in a non-linear movement, thereby moving the blocking feature is moved from a first position to a second position in an arc shaped movement. In the first state of the mechanism, the engagement preventing member is configured to prevent an engagement of the blocking member with the engagement element by covering the engagement element, and wherein, in the second state of the mechanism, the engagement element is free from the engagement preventing member such that the blocking member is enabled to engage with the engagement element.

摘要翻译： 具有第一和第二状态的药物输送装置的机构，包括接合防止构件，以及具有阻塞特征的阻挡构件和与阻挡构件接合的接合元件。 阻挡构件构造成以非线性运动与接合元件接合，从而使阻挡特征从弧形移动中的第一位置移动到第二位置。 在机构的第一状态下，接合防止构件被构造成通过覆盖接合元件来防止阻挡构件与接合元件的接合，并且其中，在机构的第二状态中，接合元件没有 接合防止构件，使得阻挡构件能够与接合元件接合。

公开(公告)号：US20160158149A1

公开(公告)日：2016-06-09

申请号：US14786460

申请日：2014-04-28

申请人： SANOFI SA

发明人： Yorick Kamlag ,  Mathias Keil

IPC分类号： A61K9/00 ,  A61K31/56 ,  A61M15/00 ,  A61K31/137

CPC分类号： A61K9/0075 ,  A61K31/137 ,  A61K31/56 ,  A61M15/0021 ,  A61M15/0065 ,  A61M15/0091 ,  A61M2202/064 ,  A61K2300/00

摘要： A pharmaceutical composition suitable for use in a dry powder inhaler comprising 70 mass %-99.5 mass % of pharmaceutically acceptable carrier suitable for use in dry powder inhalation formulation and 0.1 mass %-12.5 mass % of salmeterol xinafoate and 0.4 mass %-17.5 mass % of fluticasone propionate.

摘要翻译： 一种适用于干粉吸入器的药物组合物，其包含70质量％-99.5质量％的适用于干粉吸入制剂的药学上可接受的载体，0.1质量％-12.5质量％的沙美特罗昔萘酸盐和0.4质量％-17.5质量％ 丙酸氟替卡松。

公开(公告)号：US20140352692A1

公开(公告)日：2014-12-04

申请号：US14372010

申请日：2013-01-22

申请人： Sanofi SA

发明人： Stefan Mayer

IPC分类号： A61M15/00

CPC分类号： A61M15/0076 ,  A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0091 ,  A61M2202/064 ,  A61M2205/581 ,  A61M2205/583 ,  G06M1/04 ,  G06M1/083

摘要： The present disclosure refers to a dose counting mechanism for an inhalation device comprising a first state and a second state wherein the mechanism is alterable from the first state to the second state by a user's suction airstream. Further, the present disclosure concerns an inhalation device comprising said dose counting mechanism.

摘要翻译： 本公开涉及一种用于吸入装置的剂量计数机构，包括第一状态和第二状态，其中机构可由用户的吸入空气流从第一状态改变到第二状态。 此外，本公开涉及包括所述剂量计数机构的吸入装置。

公开(公告)号：US20130112199A1

公开(公告)日：2013-05-09

申请号：US13685745

申请日：2012-11-27

申请人： SANOFI SA

发明人： Alfred Von Schuckmann

IPC分类号： A61M15/00

CPC分类号： A61M15/0065 ,  A61M15/0006 ,  A61M2202/064

摘要： An inhaler for powdery, in particular medical, substances is formed with a suction air channel, which leads to a mouthpiece. The inhaler also has a storage chamber for storing the substance and a linearly moving dosing chamber for apportioning a specified amount of substance from the storage chamber to a transfer point to the suction air flow. The aim of the invention is to obtain a structurally simple solution that makes it possible to eliminate adding an external air flow. To this end, a component of the suction air flow, which is located in the direction of extension of the dosing chamber, empties said dosing chamber.

摘要翻译： 用于粉末状，特别是医疗物质的吸入器形成有吸气通道，其通向接口。 吸入器还具有用于储存物质的储存室和用于将特定量的物质从储存室分配到吸入空气流的转移点的线性运动计量室。 本发明的目的是获得一种结构简单的解决方案，其可以消除添加外部空气流。 为此，位于剂量室的延伸方向上的吸入空气流的一部分排空所述计量室。

公开(公告)号：US09895501B2

公开(公告)日：2018-02-20

申请号：US14021915

申请日：2013-09-09

申请人： SANOFI SA

发明人： Alfred Von Schuckmann ,  Yorick Kamlag ,  Stefan Mayer ,  Dennis Sandell

IPC分类号： A61M15/00

CPC分类号： A61M15/0065 ,  A61M15/0006 ,  A61M15/0025 ,  A61M15/0086 ,  A61M15/0091 ,  A61M2202/062 ,  A61M2202/064 ,  A61M2206/16

摘要： A metering device activated by a user induced airstream for an inhalation of a medicinal substance. The device includes: a closure cap; a piston; a mouthpiece; and an annular chamber disposed upstream of the mouthpiece. A storage chamber stores the substance which can be moved out of the storage chamber when the closure cap is removed. A metering rod for removing the medicinal substance out of the storage chamber into an emptying-standby position. In the emptying-standby position, the metering chamber is closed by the piston. The piston is displaceable by airstream into an emptying-release position. In the emptying-release position, a metering chamber is released and the substance removed by the suction airstream. The metering device includes an outer cylinder which accommodates an inner cylinder.

公开(公告)号：US20170361038A1

公开(公告)日：2017-12-21

申请号：US15542939

申请日：2016-01-13

申请人： Sanofi SA

发明人： Stefan Mayer ,  Steve Minshull

IPC分类号： A61M15/00

CPC分类号： A61M15/0081 ,  A61M5/50 ,  A61M15/0025 ,  A61M15/0065 ,  A61M15/0071 ,  A61M15/0073 ,  A61M2205/273 ,  A61M2205/583

摘要： The present disclosure concerns an assembly for a drug delivery device (1)comprising a housing (3), a first abutment surface (64), a second abutment surface (21), and a detachable member (7) which is detachable from the housing (3) and attachable to the housing (3), wherein the assembly is configured such that, during detachment of the detachable member (7) from the housing (3) for an Nth time, N being a predetermined number, the first abutment surface (64) is brought into abutment with the second abutment surface (21), wherein the assembly is configured such that, when the first abutment surface (64) abuts with the second abutment surface (21), the detachable member (7) is enabled to be reattached to the housing (3) and, afterwards, the detachable member (7) is prevented from being detached from the housing (3).

公开(公告)号：US20170182268A1

公开(公告)日：2017-06-29

申请号：US15313140

申请日：2015-05-18

申请人： SANOFI SA

发明人： Stefan MAYER

IPC分类号： A61M15/00 ,  G06M1/24

CPC分类号： A61M15/0068 ,  A61M15/0073 ,  A61M15/009 ,  A61M15/08 ,  G06M1/04 ,  G06M1/041 ,  G06M1/08 ,  G06M1/083 ,  G06M1/24 ,  G06M1/246

摘要： An assembly for a counter mechanism for a drug delivery device is described comprising a drive member, wherein the drive member is adapted and arranged to be rotated in a first rotational direction and to be prevented from rotation in a second rotational direction which direction is opposite to the first rotational direction, an advancing member adapted and arranged to be axially moved and rotated with respect to the drive member, wherein the advancing member is adapted and arranged to mechanically cooperate with the drive member such that the drive member is rotated in the first rotational direction, and a display member which is configured to count a number of doses and to display the counted number of doses, wherein the assembly is adapted and arranged such that rotation of the drive member in the first rotational direction is converted into a counting movement of the display member. Furthermore, a drug delivery device comprising the assembly is described.

公开(公告)号：US20160074318A1

公开(公告)日：2016-03-17

申请号：US14787727

申请日：2014-04-28

申请人： SANOFI SA

发明人： Yorick Kamlag ,  Mathias Keil

IPC分类号： A61K9/00 ,  A61K31/573 ,  A61M15/00 ,  A61K31/58 ,  A61K47/26 ,  A61K31/137 ,  A61K31/167

CPC分类号： A61K9/008 ,  A61K9/0075 ,  A61K31/137 ,  A61K31/167 ,  A61K31/56 ,  A61K31/573 ,  A61K31/58 ,  A61K47/26 ,  A61M15/0021 ,  A61M15/0065 ,  A61M15/0091 ,  A61M2202/064 ,  A61K2300/00

摘要： An inhalable pharmaceutical composition suitable for giving improved feedback to the patient about the inhalation of the metered doses in a range between 5 miligram and 10 miligram and suitable for use in a dry powder inhaler comprises 70 mass %-99.5 mass % of pharmaceutically acceptable carrier suitable for use in dry powder inhalation formulation and 0.5 mass %-30 mass % of one or two pharmaceutically active ingredient(s).

摘要翻译： 一种可吸入的药物组合物，其适用于向患者提供关于在5毫克至10毫克范围内吸入计量剂量并适用于干粉吸入器的改进反馈，其包含70质量％-99.5质量％的药学上可接受的载体 用于干粉吸入制剂和0.5质量％-30质量％的一种或两种药物活性成分。

公开(公告)号：US20160051777A1

公开(公告)日：2016-02-25

申请号：US14779123

申请日：2014-04-02

申请人： SANOFI SA

发明人： Stefan Mayer

IPC分类号： A61M15/00

CPC分类号： A61M15/0066 ,  A61M15/002 ,  A61M15/0065 ,  A61M2202/064 ,  A61M2205/3334

摘要： A metering element for an inhalation device is provided. The metering element comprises a plurality of openings being configured to receive a substance, wherein at least one of the openings has a different size than at least one other opening. Furthermore, an assembly for an inhalation device is provided. The assembly comprises a metering element with a plurality of openings and a powder channel which comprises an opening, wherein an arrangement of the openings is adapted to the shape of the powder channel such that each opening extends into the opening of the powder channel for a different amount.

摘要翻译： 提供了一种用于吸入装置的计量元件。 计量元件包括多个开口，其被配置为容纳物质，其中至少一个开口具有与至少一个其它开口不同的尺寸。 此外，提供了一种用于吸入装置的组件。 组件包括具有多个开口的计量元件和包括开口的粉末通道，其中开口的布置适合于粉末通道的形状，使得每个开口延伸到粉末通道的开口中以用于不同的开口 量。