公开(公告)号：US09868763B2

公开(公告)日：2018-01-16

申请号：US14235640

申请日：2012-07-27

申请人： David Fairlie ,  Ligong Liu ,  Mei-Kwan Yau ,  Jacky Yung Suen ,  Robert Reid ,  Rink-Jan Lohman ,  Abishek Venkatasubramanian Iyer ,  Junxian Lim ,  Lindsay Charles Brown

发明人： David Fairlie ,  Ligong Liu ,  Mei-Kwan Yau ,  Jacky Yung Suen ,  Robert Reid ,  Rink-Jan Lohman ,  Abishek Venkatasubramanian Iyer ,  Junxian Lim ,  Lindsay Charles Brown

IPC分类号： C07K5/08 ,  A61K38/05 ,  C07K5/065 ,  C07K5/02 ,  C07K5/06

CPC分类号： C07K5/08 ,  A61K38/05 ,  C07K5/02 ,  C07K5/06 ,  C07K5/06078

摘要： The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities.

公开(公告)号：US20140315796A1

公开(公告)日：2014-10-23

申请号：US14235640

申请日：2012-07-27

申请人： David Fairlie ,  Ligong Liu ,  Mei-Kwan Yau ,  Jacky Yung Suen ,  Robert Reid ,  Rink-Jan Lohman ,  Abishek Venkatasubramania Iyer ,  Junxian Lim ,  Lindsay Charles Brown

发明人： David Fairlie ,  Ligong Liu ,  Mei-Kwan Yau ,  Jacky Yung Suen ,  Robert Reid ,  Rink-Jan Lohman ,  Abishek Venkatasubramania Iyer ,  Junxian Lim ,  Lindsay Charles Brown

IPC分类号： C07K5/08 ,  C07K5/02 ,  C07K5/06

CPC分类号： C07K5/08 ,  A61K38/05 ,  C07K5/02 ,  C07K5/06 ,  C07K5/06078

摘要： The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities.

摘要翻译： 本发明提供新的式（I）化合物，包含这些化合物的药物组合物和使用这些化合物作为生物学研究的工具的方法，或作为代谢综合征，肥胖症，II型糖尿病，纤维化和心血管疾病的治疗药物或药物 疾病，无论是单独使用还是与其他治疗方式结合使用。