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Patent Agency Ranking
公开(公告)号：US08420646B2
公开(公告)日：2013-04-16
申请号：US12972921
申请日：2010-12-20
Applicant: Michael Robert Barbachyn , Paul Joseph Dobrowolski , Alexander Ross Hurd , Dennis Joseph McNamara , John Raymond Palmer , Arthur Glenn Romero , J. Craig Ruble , Debra Ann Sherry , Lisa Marie Thomasco , Peter Laurence Toogood
Inventor： Michael Robert Barbachyn , Paul Joseph Dobrowolski , Alexander Ross Hurd , Dennis Joseph McNamara , John Raymond Palmer , Arthur Glenn Romero , J. Craig Ruble , Debra Ann Sherry , Lisa Marie Thomasco , Peter Laurence Toogood
IPC: A61K31/5383 , A61K31/527 , C07D498/20 , C07D471/20 , C07D498/04
CPC classification number: C07D471/20 , C07D498/10 , C07D498/20
Abstract: The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R5, R20 and X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
Abstract translation: 本发明涉及式I的三环四氢喹啉化合物及其药学上可接受的盐，其中变量R1，R2，R3，R4，R5，R20和X如本文所述及其药物组合物，其对抗 广泛的人类和兽医病原体。
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公开(公告)号：US20100022524A1
公开(公告)日：2010-01-28
申请号：US12549407
申请日：2009-08-28
Applicant: Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
Inventor： Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
IPC: A61K31/5386 , C07D498/20 , C07D471/20 , A61P31/00 , A61K31/499 , A61P3/04
CPC classification number: C07D471/20 , C07D498/10 , C07D498/20
Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
Abstract translation: 本发明包括四氢喹啉和相关的式I化合物及其药物组合物，其对广泛范围的人和兽医病原体表现出有用的抗菌活性。
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公开(公告)号：US20110092494A1
公开(公告)日：2011-04-21
申请号：US12972921
申请日：2010-12-20
Applicant: Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
Inventor： Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
IPC: A61K31/5383 , C07D498/20 , C07D471/20 , C07D498/04 , A61K31/527 , A61P31/00
CPC classification number: C07D471/20 , C07D498/10 , C07D498/20
Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
Abstract translation: 本发明包括四氢喹啉和相关的式I化合物及其药物组合物，其对广泛范围的人和兽医病原体表现出有用的抗菌活性。
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公开(公告)号：US07605157B2
公开(公告)日：2009-10-20
申请号：US11715213
申请日：2007-03-07
Applicant: Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
Inventor： Michael Robert Barbachyn , J. Craig Ruble , Arthur Glenn Romero , Lisa Marie Thomasco , Alexander Ross Hurd , John Raymond Palmer , Peter Laurence Toogood , Dennis Joseph McNamara , Debra Ann Sherry , Paul Joseph Dobrowolski
IPC: C07D491/10 , C07D487/10 , A61K31/499 , A61K31/5386
CPC classification number: C07D471/20 , C07D498/10 , C07D498/20
Abstract: The invention includes tetrahydroquinoline and related compounds of formula I and pharmaceutical compositions thereof, that exhibit useful antibacterial activity again a wide range of human and veterinary pathogens
Abstract translation: 本发明包括四氢喹啉和相关的式I化合物及其药物组合物，再次显示出广泛的人类和兽医病原体的有用的抗菌活性
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公开(公告)号：US07208490B2
公开(公告)日：2007-04-24
申请号：US10677551
申请日：2003-10-02
Applicant: Michael Robert Barbachyn , Gordan L. Bundy , Paul Joseph Dobrowolski , Alexander Ross Hurd , Gary E. Martin , Dennis Joseph McNamara , John Raymond Palmer , Donna L. Romero , Arthur Glenn Romero , J. Craig Ruble , Debra Ann Sherry , Lisa Marie Thomasco , Peter Laurence Toogood
Inventor： Michael Robert Barbachyn , Gordan L. Bundy , Paul Joseph Dobrowolski , Alexander Ross Hurd , Gary E. Martin , Dennis Joseph McNamara , John Raymond Palmer , Donna L. Romero , Arthur Glenn Romero , J. Craig Ruble , Debra Ann Sherry , Lisa Marie Thomasco , Peter Laurence Toogood
IPC: C07D491/10 , C07D487/10 , A61K31/499 , A61K31/5386
CPC classification number: C07D471/20 , C07D498/10 , C07D498/20
Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens
Abstract translation: 本发明包括四氢喹啉和相关的式I化合物及其药物组合物，其对广泛的人和兽医病原体表现出有用的抗菌活性
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