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公开(公告)号：US11370773B1
公开(公告)日：2022-06-28
申请号：US17378282
申请日：2021-07-16
发明人： Matthew G. Bursavich , Dan Cui , James E. Dowling , Kristopher N. Hahn , Bryce A. Harrison , Fu-Yang Lin , Blaise S. Lippa , Bruce N. Rogers , Dawn M. Troast , Cheng Zhong , Kyle D. Konze , Aleksey I. Gerasyuto , Byungchan Kim , Salma Rafi , Tyler Day , Eugene Hickey , Evelyne Houang , Robert Zahler
IPC分类号： C07D401/06 , C07D213/64
摘要： Disclosed are small molecule antagonists of human α4β7 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US10759756B2
公开(公告)日：2020-09-01
申请号：US16382512
申请日：2019-04-12
发明人： Matthew G. Bursavich , Dawn M. Troast , Bryce A. Harrison , Blaise S. Lippa , Bruce N. Rogers , Kyle D. Konze , Aleksey I. Gerasyuto , Tyler Day , Fu-Yang Lin , Kristopher N. Hahn , Mats A. Svensson , Byungchan Kim , Cheng Zhong , Alexey A. Lugovskoy , Brian Sosa
IPC分类号： C07D401/12 , C07D401/14 , C07D213/64 , C07D401/06 , C07D413/14 , C07D241/18 , C07D413/12 , C07D487/04 , C07D239/90 , C07D237/32 , C07D205/08 , C07D471/04
摘要： Disclosed are small molecule antagonists of α4β7 integrin, and methods of using them to treat a number of specific diseases or conditions.
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公开(公告)号：US20240294475A1
公开(公告)日：2024-09-05
申请号：US18394421
申请日：2023-12-22
发明人： Matthew G. Bursavich , Dawn M. Troast , Bryce A. Harrison , Blaise S. Lippa , Bruce N. Rogers , Kyle D. Konze , Aleksey I. Gerasyuto , Tyler Day , Fu-Yang Lin , Kristopher N. Hahn , Mats A. Svensson , Byungchan Kim , Cheng Zhong , Alexey A. Lugovskoy , Brian Sosa
IPC分类号： C07D213/64 , C07D205/08 , C07D237/32 , C07D239/90 , C07D241/18 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04
CPC分类号： C07D213/64 , C07D205/08 , C07D237/32 , C07D239/90 , C07D241/18 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/12 , C07D413/14 , C07D471/04 , C07D487/04
摘要： Disclosed are small molecule antagonists of α4β7 integrin, and methods of using them to treat a number of specific diseases or conditions.
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公开(公告)号：US11739087B2
公开(公告)日：2023-08-29
申请号：US17239045
申请日：2021-04-23
发明人： Bryce A. Harrison , James E. Dowling , Matthew G. Bursavich , Dawn M. Troast , Blaise S. Lippa , Bruce N. Rogers , Kristopher N. Hahn , Cheng Zhong , Qi Qiao , Fu-Yang Lin , Brian Sosa , Aleksey I. Gerasyuto , Andrea Bortolato , Mats A. Svensson , Eugene Hickey , Kyle D. Konze , Tyler Day , Byungchan Kim
IPC分类号： C07D471/04 , A61K9/00
CPC分类号： C07D471/04 , A61K9/0053
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US20230242524A1
公开(公告)日：2023-08-03
申请号：US17967346
申请日：2022-10-17
发明人： Bryce A. Harrison , James E. Dowling , Aleksey I. Gerasyuto , Matthew G. Bursavich , Dawn M. Troast , Blaise S. Lippa , Bruce N. Rogers , Cheng Zhong , Fu-Yang Lin , Brian Sosa , Andrea Bortolato , Mats A. Svensson , Eugene Hickey , Kyle D. Konze , Tyler Day , Byungchan Kim
IPC分类号： C07D471/04 , A61K9/00 , C07D519/00
CPC分类号： C07D471/04 , A61K9/0053 , C07D519/00
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US11104661B1
公开(公告)日：2021-08-31
申请号：US17072797
申请日：2020-10-16
发明人： Matthew G. Bursavich , Dan Cui , James E. Dowling , Kristopher N. Hahn , Bryce A. Harrison , Fu-Yang Lin , Blaise S. Lippa , Bruce N. Rogers , Dawn M. Troast , Cheng Zhong , Kyle D. Konze , Aleksey I. Gerasyuto , Byungchan Kim , Salma Rafi , Tyler Day , Eugene Hickey , Evelyne Houang , Robert Zahler
IPC分类号： C07D401/06 , C07D213/64
摘要： Disclosed are small molecule antagonists of human α4β7 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US11046669B2
公开(公告)日：2021-06-29
申请号：US16453418
申请日：2019-06-26
发明人： Bryce A. Harrison , Matthew G. Bursavich , Mark Brewer , Aleksey I. Gerasyuto , Kristopher N. Hahn , Kyle D. Konze , Fu-Yang Lin , Blaise S. Lippa , Alexey A. Lugovskoy , Bruce N. Rogers , Mats A. Svensson , Dawn M. Troast
IPC分类号： C07D471/04 , C07D401/12 , C07D519/00 , C07D471/08 , C07D487/08
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US20200071322A1
公开(公告)日：2020-03-05
申请号：US16555589
申请日：2019-08-29
发明人： Bryce A. Harrison , James E. Dowling , Matthew G. Bursavich , Dawn M. Troast , Blaise S. Lippa , Bruce N. Rogers , Kristopher N. Hahn , Cheng Zhong , Qi Qiao , Fu-Yang Lin , Brian Sosa , Aleksey I. Gerasyuto , Andrea Bortolato , Mats A. Svensson , Eugene Hickey , Kyle D. Konze , Tyler Day , Byungchan Kim
IPC分类号： C07D471/04 , A61K9/00
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US20230219947A1
公开(公告)日：2023-07-13
申请号：US17967342
申请日：2022-10-17
发明人： Bryce A. Harrison , James E. Dowling , Aleksey I. Gerasyuto , Matthew G. Bursavich , Dawn M. Troast , Blaise S. Lippa , Bruce N. Rogers , Cheng Zhong , Qi Qiao , Fu-Yang Lin , Brian Sosa , Andrea Bortolato , Mats A. Svensson , Eugene Hickey , Kyle D. Konze , Tyler Day , Byungchan Kim
IPC分类号： C07D471/04 , C07D519/00 , A61K9/00
CPC分类号： C07D471/04 , C07D519/00 , A61K9/0053
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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公开(公告)号：US20220073511A1
公开(公告)日：2022-03-10
申请号：US17239045
申请日：2021-04-23
发明人： Bryce A. Harrison , James E. Dowling , Matthew G. Bursavich , Dawn M. Troast , Blaise S. Lippa , Bruce N. Rogers , Kristopher N. Hahn , Cheng Zhong , Qi Qiao , Fu-Yang Lin , Brian Sosa , Aleksey I. Gerasyuto , Andrea Bortolato , Mats A. Svensson , Eugene Hickey , Kyle D. Konze , Tyler Day , Byungchan Kim
IPC分类号： C07D471/04 , A61K9/00
摘要： Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.
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