公开(公告)号：US4013649A

公开(公告)日：1977-03-22

申请号：US514259

申请日：1974-10-11

申请人： Mitchell Joseph Bogdanowicz, Jr.

发明人： Mitchell Joseph Bogdanowicz, Jr.

IPC分类号： C07C53/19 ,  C07D253/06

CPC分类号： C07C53/19 ,  C07D253/06

摘要： Method of making 4-amino-6-t-butyl-3-mercapto-1,2,4-triazin-5-one comprising halogenating a 3,3-dimethylbutyric acid with Br.sub.2 or Cl.sub.2 to produce a 2,2-dihalo-3,3-dimethylbutyric acid then reacting the latter with thiocarbohydrazide. Alternatively, a 3,3-dimethylbutyryl chloride can be used as starting material, in which case the halogenation product is contacted with water, an aqueous base, an alcohol, a mercaptan, or an amine to convert it to an acid or salt thereof, anhydride, ester, thioester or amide, and the latter is reacted with thiocarbohydrazide.