公开(公告)号：US07857775B2

公开(公告)日：2010-12-28

申请号：US11079887

申请日：2005-03-15

申请人： Avner Rosenberg ,  Michael Kreindel

发明人： Avner Rosenberg ,  Michael Kreindel

IPC分类号： A61H7/00 ,  A61H23/00

CPC分类号： A61H23/0236 ,  A61H2201/165 ,  A61N7/00 ,  A61N7/02 ,  A61N2007/0008

摘要： A method and system for non-invasive treatment of a soft tissue, such as adipose tissue, muscle tissue or connective tissue. The apparatus comprises an applicator configured to apply a pressure pulse to the skin surface having a negative pressure phase with respect to ambient pressure. The method comprises applying at least one pressure pulse to the skin surface overlying the soft tissue, where the pressure pulse has at least one negative pressure phase.

摘要翻译： 用于软组织如脂肪组织，肌肉组织或结缔组织的非侵入性治疗的方法和系统。 该装置包括施加器，其构造成将压力脉冲施加到具有相对于环境压力的负压相位的皮肤表面。 该方法包括向覆盖软组织的皮肤表面施加至少一个压力脉冲，其中压力脉冲具有至少一个负压相位。

公开(公告)号：US20100198199A1

公开(公告)日：2010-08-05

申请号：US12451979

申请日：2008-06-11

申请人： Michael Kreindel

发明人： Michael Kreindel

IPC分类号： A61B18/18

CPC分类号： A61B18/14 ,  A61B18/203 ,  A61B2018/00452 ,  A61B2018/00994 ,  A61B2018/1807

摘要： The presently described subject matter provides a method and system for heating a skin area surface of an individual from an initial temperature to a treatment temperature in a treatment time period exceeding 0.5 sec, where the treatment temperature is in the range of 40°-60° C. An RF generator provides a continuous wave RF voltage energy or a quasi-continuous wave RF voltage across first and second electrode, where at least the first electrode is associated with an applicator that is displaced over the skin surface. The system further includes a skin temperature measuring device or an applicator displacement speed measuring device; and a CPU that monitors a skin temperature or an applicator displacement speed. The CPU turns off the RF energy when the skin temperature is above a predetermined temperature or the displacement speed of the applicator is below a predetermined speed, in order to prevent overheating of the skin.

摘要翻译： 目前描述的主题提供了一种在超过0.5秒的处理时间内将个体的皮肤区域表面从初始温度加热到处理温度的方法和系统，其中处理温度在40°-60°的范围内 C.RF发生器提供跨越第一和第二电极的连续波RF电压能量或准连续波RF电压，其中至少第一电极与在皮肤表面上移位的施加器相关联。 该系统还包括皮肤温度测量装置或涂抹器位移速度测量装置; 以及监视皮肤温度或涂抹器位移速度的CPU。 当皮肤温度高于预定温度或者涂抹器的位移速度低于预定速度时，CPU关闭RF能量，以防止皮肤过热。

公开(公告)号：US07238183B2

公开(公告)日：2007-07-03

申请号：US10774478

申请日：2004-02-10

申请人： Michael Kreindel

发明人： Michael Kreindel

IPC分类号： A61B18/18

CPC分类号： A61B18/14 ,  A61B2018/00023 ,  A61B2018/00452

摘要： System and method for treating a skin target. A temperature effector creates a temperature difference between the target and the skin tissue surrounding the target such that the target is at a higher temperature than the surrounding tissue by at least 5° C. One or more RF electrodes are attached to the skin and RF energy is applied.

摘要翻译： 用于治疗皮肤靶的系统和方法。 温度效应器在目标和靶标周围的皮肤组织之间产生温度差异，使得靶在比周围组织更高的温度下至少5℃。一个或多个RF电极附着于皮肤和RF能量 被申请;被应用。

公开(公告)号：US20060211958A1

公开(公告)日：2006-09-21

申请号：US11079887

申请日：2005-03-15

申请人： Avner Rosenberg ,  Michael Kreindel

发明人： Avner Rosenberg ,  Michael Kreindel

IPC分类号： A61H7/00

CPC分类号： A61H23/0236 ,  A61H2201/165 ,  A61N7/00 ,  A61N7/02 ,  A61N2007/0008

摘要： A method and system for non-invasive treatment of a soft tissue, such as adipose tissue, muscle tissue or connective tissue. The apparatus comprises an applicator configured to apply a pressure pulse to the skin surface having a negative pressure phase with respect to ambient pressure. The method comprises applying at least one pressure pulse to the skin surface overlying the soft tissue, where the pressure pulse has at least one negative pressure phase.

摘要翻译： 用于软组织如脂肪组织，肌肉组织或结缔组织的非侵入性治疗的方法和系统。 该装置包括施加器，其构造成将压力脉冲施加到具有相对于环境压力的负压相位的皮肤表面。 该方法包括向覆盖软组织的皮肤表面施加至少一个压力脉冲，其中压力脉冲具有至少一个负压相位。

公开(公告)号：US6162212A

公开(公告)日：2000-12-19

申请号：US294753

申请日：1999-04-19

申请人： Michael Kreindel ,  Shimon Eckhouse

发明人： Michael Kreindel ,  Shimon Eckhouse

IPC分类号： A61B18/20 ,  A61B18/18

CPC分类号： A61B18/203 ,  A61B2018/00452 ,  A61B2018/00476

摘要： A method for determining an optimal plan of sessions for hair removal treatment. The method includes the steps of receiving information about a hair growth cycle duration of a person to be treated, a duration of the Anagen stage of the person and at least one parameter of a device to be used for performing the treatment, and processing the received information thereby determining at least one of the group including the optimal number of hair removal tretament sessions and the optimal delay between sessions of the treatment.

摘要翻译： 一种用于确定脱毛治疗的最佳疗程计划的方法。 该方法包括以下步骤：接收关于待治疗的人的毛发生长周期持续时间的信息，人的Anagen阶段的持续时间和用于执行治疗的装置的至少一个参数，以及处理所接收的 信息，从而确定组中的至少一个，包括最佳毛发去除时间段的次数以及治疗期间之间的最佳延迟。

公开(公告)号：US5833612A

公开(公告)日：1998-11-10

申请号：US594891

申请日：1996-02-09

申请人： Shimon Eckhouse ,  Michael Kreindel

发明人： Shimon Eckhouse ,  Michael Kreindel

IPC分类号： A61B5/00 ,  A61B5/103 ,  A61B10/00

CPC分类号： A61B5/441 ,  A61B5/0059 ,  A61B2562/0242 ,  A61B5/0062

摘要： A method and apparatus for determining skin lesion parameters comprise directing light to the skin in which the lesion is located and monitoring the reflection of that light. Then, the spatial and spectral distribution of the reflected light is analyzed. The depth is determined by finding a location where the difference between a spectral intensity of reflected light and an average reflected intensity is greater than a maximal difference between the intensity of each point and an average intensity for normal skin. The wavelength of the light reflected from the location is determined, and from the wavelength the penetration depth is determined. The penetration depth is also the depth of the lesion below the skin surface. The size is determined by determining a plurality of locations where the deviation between the spectral intensity and the average intensity is greater than the maximal deviation for normal skin. Based on the spatial distribution of the locations the size of the lesion is determined.

摘要翻译： 用于确定皮肤损伤参数的方法和装置包括将光引导到病变位于其中的皮肤并监测该光的反射。 然后，分析反射光的空间和光谱分布。 通过找到反射光的光谱强度和平均反射强度之间的差异大于每个点的强度与正常皮肤的平均强度之间的最大差异的位置来确定深度。 确定从该位置反射的光的波长，并从波长确定穿透深度。 穿透深度也是皮肤表面下方病变的深度。 通过确定光谱强度和平均强度之间的偏差大于正常皮肤的最大偏差的多个位置来确定尺寸。 基于位置的空间分布，确定病变的大小。

公开(公告)号：US5776175A

公开(公告)日：1998-07-07

申请号：US536985

申请日：1995-09-29

申请人： Shimon Eckhouse ,  Michael Kreindel

发明人： Shimon Eckhouse ,  Michael Kreindel

IPC分类号： A61B18/00 ,  A61N5/06 ,  A61F2/00

CPC分类号： A61N5/06 ,  A61N5/0616 ,  A61N2005/0644 ,  A61N2005/0659

摘要： The invention includes a method for the hyperthermic treatment of tumors including the steps of providing a pulsed radiation output from a radiation source; and directing said pulsed radiation output toward a tumor. The invention further includes an apparatus for the treatment of tumors having a radiation source adapted to produce broad-band pulsed radiation output at least in the visible and near-infrared range of wavelengths, a delivery system proximal to the radiation source and adapted to focus and direct the pulsed radiation output to a dermal treatment site, and a filtering system adapted to restrict the pulsed radiation output to bands in the visible and near-infrared range of wavelengths.

摘要翻译： 本发明包括用于高热治疗肿瘤的方法，包括从辐射源提供脉冲辐射输出的步骤; 并将所述脉冲辐射输出引向肿瘤。 本发明还包括一种用于治疗肿瘤的装置，其具有适于产生至少在可见光和近红外波长范围内的宽带脉冲辐射输出的辐射源，靠近辐射源的输送系统，并适于聚焦和 将脉冲辐射输出引导到皮肤处理部位，以及适于将脉冲辐射输出限制在可见光和近红外波长范围内的滤光系统。

公开(公告)号：US08900231B2

公开(公告)日：2014-12-02

申请号：US12702647

申请日：2010-02-09

申请人： Michael Kreindel

发明人： Michael Kreindel

IPC分类号： A61B18/14 ,  A61B18/18 ,  A61B18/00

CPC分类号： A61B18/18 ,  A61B18/0218 ,  A61B18/14 ,  A61B18/1477 ,  A61B2018/00452 ,  A61B2018/0293 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1467

摘要： A system and method for simultaneously heating a plurality of discrete skin volumes to a coagulation temperature. The system comprises an applicator containing an electrode having a plurality of spaced apart protruding conducting elements configured to contact the skin surface at a plurality of discrete locations. A controller applies a voltage to the electrode so as to simultaneously heat a plurality of skin volumes to a coagulation temperature when the applicator is applied to the skin surface.

摘要翻译： 一种用于将多个离散皮肤体积同时加热至凝固温度的系统和方法。 该系统包括施加器，其包含具有多个间隔开的突出导电元件的电极，该导电元件被配置为在多个离散位置处接触皮肤表面。 控制器向电极施加电压，以便当施加器施加到皮肤表面时同时将多个皮肤体积加热到凝固温度。

公开(公告)号：US20130289554A1

公开(公告)日：2013-10-31

申请号：US13925832

申请日：2013-06-25

申请人： Michael Kreindel

发明人： Michael Kreindel

IPC分类号： A61B18/18

CPC分类号： A61B18/18 ,  A61B18/0218 ,  A61B18/14 ,  A61B18/1477 ,  A61B2018/00452 ,  A61B2018/0293 ,  A61B2018/1425 ,  A61B2018/143 ,  A61B2018/1467

摘要： A system and method for simultaneously heating a plurality of discrete skin volumes to a coagulation temperature. The system comprises an applicator containing an electrode having a plurality of spaced apart protruding conducting elements configured to contact the skin surface at a plurality of discrete locations. A controller applies a voltage to the electrode so as to simultaneously heat a plurality of skin volumes to a coagulation temperature when the applicator is applied to the skin surface.

摘要翻译： 一种用于将多个离散皮肤体积同时加热至凝固温度的系统和方法。 该系统包括施加器，其包含具有多个间隔开的突出导电元件的电极，该导电元件被配置为在多个离散位置处接触皮肤表面。 控制器向电极施加电压，以便当施加器施加到皮肤表面时同时将多个皮肤体积加热到凝固温度。

公开(公告)号：US08133191B2

公开(公告)日：2012-03-13

申请号：US11355181

申请日：2006-02-16

申请人： Avner Rosenberg ,  Shimon Eckhouse ,  Michael Kreindel

发明人： Avner Rosenberg ,  Shimon Eckhouse ,  Michael Kreindel

IPC分类号： A61N7/00

CPC分类号： A61N7/00 ,  A61B18/12 ,  A61B2017/00026 ,  A61B2017/00061 ,  A61B2017/00106 ,  A61B2018/0047 ,  A61B2090/378 ,  A61N1/0408 ,  A61N1/0472 ,  A61N1/328 ,  A61N2007/0008 ,  A61N2007/0039 ,  A61N2007/0078

摘要： The invention provides methods and apparatuses for the treatment of adipose tissue. The methods comprise application of ultrasound energy to a region of adipose tissue, and the apparatuses comprise at least one source of ultrasound energy configured to direct ultrasound energy through a skin surface into the subcutaneous adipose tissue. In one embodiment, a pressure gradient is created in the region generating relative movement between fat cell constituents having different densities. In another embodiment, a protrusion of skin and underlying adipose tissue containing is formed and ultrasound energy is radiated into the adipose tissue in the protrusion. In another embodiment, an RF electric field is generated inside a region of adipose tissue together with the ultrasound energy.

摘要翻译： 本发明提供了用于治疗脂肪组织的方法和装置。 所述方法包括将超声能量应用于脂肪组织的区域，并且所述装置包括至少一个超声能量源，其被配置为将超声能量通过皮肤表面引导到皮下脂肪组织中。 在一个实施例中，在产生具有不同密度的脂肪细胞组分之间产生相对运动的区域中产生压力梯度。 在另一个实施方案中，形成皮肤的突起和包含的下面的脂肪组织，并且将超声能量辐射到突起中的脂肪组织中。 在另一个实施例中，在脂肪组织的区域内与超声波能量一起产生RF电场。