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公开(公告)号：US5652119A
公开(公告)日：1997-07-29
申请号：US663871
申请日：1996-06-19
IPC分类号： A61K39/245 , A61K39/00 , A61K39/265 , A61K39/29 , A61K39/295 , A61P31/12 , A61P31/22 , C07K14/00 , C07K14/03 , C07K14/15 , C07K14/155 , C12N5/10 , C12N7/00 , C12N7/01 , C12N7/04 , C12N15/09 , C12N15/31 , C12N15/38 , C12N15/62 , C12N15/86 , C12N15/869 , C12P21/00 , A61K39/12
CPC分类号： C07K14/005 , A61K39/12 , A61K39/245 , C12N15/86 , C12N7/00 , A61K2039/5254 , A61K2039/5256 , A61K39/00 , C12N2710/16722 , C12N2710/16734 , C12N2710/16743 , C12N2710/16762 , C12N2740/13022 , C12N2740/15022
摘要： The present invention is concerned with a Feline herpesvirus (FHV) mutant comprising a heterologous gene introduced into an insertion-region of the FHV genome.The invention also relates to a vector vaccine comprising such an FHV mutant which expresses a heterologous polypeptide derived from a feline pathogen and induces an adequate immune response in an inoculated host against both FHV and the feline pathogen.
摘要翻译： 本发明涉及包含引入FHV基因组插入区域的异源基因的猫疱疹病毒（FHV）突变体。 本发明还涉及包含这样的FHV突变体的载体疫苗，其表达源自猫科病原体的异源多肽，并且在接种的宿主中对FHV和猫病原体诱导足够的免疫应答。
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公开(公告)号：US5783192A
公开(公告)日：1998-07-21
申请号：US664894
申请日：1996-07-17
IPC分类号： A61K39/245 , A61K39/00 , A61K39/265 , A61K39/29 , A61K39/295 , A61P31/12 , A61P31/22 , C07K14/00 , C07K14/03 , C07K14/15 , C07K14/155 , C12N5/10 , C12N7/00 , C12N7/01 , C12N7/04 , C12N15/09 , C12N15/31 , C12N15/38 , C12N15/62 , C12N15/86 , C12N15/869 , C12P21/00 , A61K39/12
CPC分类号： C07K14/005 , A61K39/12 , A61K39/245 , C12N15/86 , C12N7/00 , A61K2039/5254 , A61K2039/5256 , A61K39/00 , C12N2710/16722 , C12N2710/16734 , C12N2710/16743 , C12N2710/16762 , C12N2740/13022 , C12N2740/15022
摘要： The present invention is concerned with a Feline herpesvirus (FHV) mutant comprising a heterologous gene introduced into an insertion-region of the FHV genome. The invention also relates to a vector vaccine comprising such an FHV mutant which expresses a heterologous polypeptide derived from a feline pathogen and induces an adequate immune response in an inoculated host against both FHV and the feline pathogen.
摘要翻译： 本发明涉及包含引入FHV基因组插入区域的异源基因的猫疱疹病毒（FHV）突变体。 本发明还涉及包含这样的FHV突变体的载体疫苗，其表达源自猫科病原体的异源多肽，并且在接种的宿主中对FHV和猫病原体诱导足够的免疫应答。
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公开(公告)号：US06521236B1
公开(公告)日：2003-02-18
申请号：US08504617
申请日：1995-07-20
IPC分类号： A61K39245
CPC分类号： C12N15/86 , A61K39/00 , C07K14/005 , C12N2710/16722 , C12N2710/16743
摘要： The present invention is concerned with a Feline Herpesvirus (FHV) mutant comprising a heterologous gene or foreign DNA inserted into a section of the FHV genome. The invention also relates to a vector vaccine comprising a recombinant FHV mutant which expresses a heterologous polypeptide derived from a feline pathogen and a pharmaceutically acceptable carrier and induces an immune response in an inoculated host against both FHV and the feline pathogen.
摘要翻译： 本发明涉及包含插入到FHV基因组的一部分中的异源基因或外来DNA的猫疱疹病毒（FHV）突变体。 本发明还涉及一种载体疫苗，其包含重组FHV突变体，其表达源自猫科病原体的异源多肽和药学上可接受的载体，并且在接种宿主中针对FHV和猫病原体诱导免疫应答。
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公开(公告)号：US5674499A
公开(公告)日：1997-10-07
申请号：US360103
申请日：1994-12-20
IPC分类号： C12N15/09 , A61K39/245 , A61P31/12 , C07K14/03 , C12N5/00 , C12N5/10 , C12N7/00 , C12N15/38 , C12R1/91 , A61K39/27 , A61K39/295
CPC分类号： C07K14/005 , C12N2710/16734
摘要： The present invention relates to an Equine herpesvirus (EHV) vaccine comprising an EHV having an insertion or deletion in the gene 15 of the EHV genome.
摘要翻译： 本发明涉及包含在EHV基因组的基因15中具有插入或缺失的EHV的马疱疹病毒（EHV）疫苗。
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