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公开(公告)号:US07314626B2
公开(公告)日:2008-01-01
申请号:US10270010
申请日:2002-10-15
IPC分类号: A61K39/00 , A61K39/12 , A61K39/145 , A61K39/385 , A61K47/00 , A61K38/00 , C12P21/00 , C12N15/09
CPC分类号: A61K39/12 , A61K39/04 , A61K39/385 , A61K47/64 , A61K2039/6031 , C07H21/04 , C07K7/06 , C07K7/08 , C12N2760/16022 , C12N2760/16034 , Y02A50/386 , Y02A50/388 , Y02A50/401 , Y02A50/403 , Y02A50/41 , Y02A50/414
摘要: The invention relates to conjugates of an antigen coupled to a linear derivative of a β-stranded antibiotic peptide, which are useful for immunogenic agents to enhance a CTL response. Two groups of preferred peptides are derived from the antibiotics protegrin and tachyplesin.
摘要翻译: 本发明涉及与β-链抗生素肽的线性衍生物偶联的抗原的缀合物,其可用于免疫原性剂以增强CTL应答。 两组优选的肽源自抗生素protegrin和tachyplesin。