公开(公告)号：US20160311877A1

公开(公告)日：2016-10-27

申请号：US15105298

申请日：2014-12-18

Applicant: Alexander WATTERS ,  Donald INGBER ,  Mark CARTWRIGHT ,  Michael SUPER ,  Martin ROTTMAN ,  PRESIDENT AND FELLOWS OF HARVARD COLLEGE

Inventor： Alexander WATTERS ,  Donald INGBER ,  Mark CARTWRIGHT ,  Michael SUPER ,  Martin ROTTMAN ,  Evangelina MURRAY ,  Brendon DUSEL

IPC: C07K14/47 ,  A61K47/42 ,  G01N33/569

Abstract: Described herein are engineered microbe-targeting molecules, microbe-targeting articles, kits comprising the same, and uses thereof. Such microbe-targeting molecules, microbe-targeting articles, or the kits comprising the same can bind or capture of a microbe or microbial matter thereof, and can thus be used in various applications, such as diagnosis or treatment of an infection caused by microbes in a subject or any environmental surface.

Abstract translation: 本文描述了工程化的微生物靶向分子，微生物靶向制品，包含其的试剂盒及其用途。 这样的微生物靶向分子，微生物靶向制品或包含其的试剂盒可以结合或捕获其微生物或微生物物质，因此可以用于各种应用中，例如诊断或治疗由微生物引起的感染 主题或任何环境表面。

公开(公告)号：US08307937B2

公开(公告)日：2012-11-13

申请号：US12704555

申请日：2010-02-12

Applicant: Daniel E. Williams ,  Mark Cartwright

Inventor： Daniel E. Williams ,  Mark Cartwright

IPC: B62D7/14 ,  B62D5/06

CPC classification number: B62D5/12 ,  B62D7/148 ,  B62D7/1563 ,  F15B15/1476

Abstract: An improved apparatus (30) for steering rear wheels (16, 18) of a vehicle (10) includes hydraulic motor (34) having chambers (56, 58) which hold hydraulic fluid. An increase in fluid pressure in one of the chambers turns the steerable rear wheels of the vehicle in a first direction. An increase in fluid pressure in another one of the chambers turns the steerable rear wheels in a second direction. A control valve (36) is connected in fluid communication with the chambers (56, 58) of the hydraulic motor. The control valve (36) is free of a return flow of hydraulic fluid from the motor (34). A return conduit (134) is connected with the chambers (56, 58) and conducts a flow of hydraulic fluid to a reservoir (116) along a path which is spaced from the control valve (36). The motor (34) may include springs (70, 72) which are disposed in the chambers (56, 58) of the motor. Biasing sleeves (76, 78) are effective to transmit force from the springs to a piston (62).

Abstract translation: 用于转向车辆（10）的后轮（16,18）的改进的装置（30）包括具有容纳液压流体的腔室（56,58）的液压马达（34）。 其中一个室中的流体压力的增加使车辆的可转向后轮沿第一方向转动。 在另一个室中的流体压力的增加使可转向后轮沿第二方向转动。 控制阀（36）与液压马达的腔室（56,58）流体连通地连接。 控制阀（36）没有来自马达（34）的液压流体的回流。 返回管道（134）与腔室（56,58）连接，并且沿着与控制阀（36）间隔开的路径将液压流体流动到储存器（116）。 马达（34）可以包括设置在马达的腔室（56,58）中的弹簧（70,72）。 偏置套筒（76,78）有效地将力从弹簧传递到活塞（62）。

公开(公告)号：US20110198146A1

公开(公告)日：2011-08-18

申请号：US12704555

申请日：2010-02-12

Applicant: Daniel E. Williams ,  Mark Cartwright

Inventor： Daniel E. Williams ,  Mark Cartwright

IPC: B62D5/12

CPC classification number: B62D5/12 ,  B62D7/148 ,  B62D7/1563 ,  F15B15/1476

Abstract: An improved apparatus (30) for steering rear wheels (16, 18) of a vehicle (10) includes hydraulic motor (34) having chambers (56, 58) which hold hydraulic fluid. An increase in fluid pressure in one of the chambers turns the steerable rear wheels of the vehicle in a first direction. An increase in fluid pressure in another one of the chambers turns the steerable rear wheels in a second direction. A control valve (36) is connected in fluid communication with the chambers (56, 58) of the hydraulic motor. The control valve (36) is free of a return flow of hydraulic fluid from the motor (34). A return conduit (134) is connected with the chambers (56, 58) and conducts a flow of hydraulic fluid to a reservoir (116) along a path which is spaced from the control valve (36). The motor (34) may include springs (70, 72) which are disposed in the chambers (56, 58) of the motor. Biasing sleeves (76, 78) are effective to transmit force from the springs to a piston (62).

Abstract translation: 用于转向车辆（10）的后轮（16,18）的改进的装置（30）包括具有容纳液压流体的腔室（56,58）的液压马达（34）。 其中一个室中的流体压力的增加使车辆的可转向后轮沿第一方向转动。 在另一个室中的流体压力的增加使可转向的后轮沿第二方向转动。 控制阀（36）与液压马达的腔室（56,58）流体连通地连接。 控制阀（36）没有来自马达（34）的液压流体的回流。 返回管道（134）与腔室（56,58）连接，并且沿着与控制阀（36）间隔开的路径将液压流体流动到储存器（116）。 马达（34）可以包括设置在马达的腔室（56,58）中的弹簧（70,72）。 偏置套筒（76,78）有效地将力从弹簧传递到活塞（62）。