公开(公告)号：US07205340B2

公开(公告)日：2007-04-17

申请号：US10240978

申请日：2001-04-06

申请人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

发明人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

IPC分类号： A61L2/00

CPC分类号： B82Y5/00 ,  A61K8/02 ,  A61K2800/413 ,  A61Q13/00 ,  C08F2/44 ,  C11D3/505 ,  C11D17/0039 ,  Y10T428/2984

摘要： The polymeric nanoparticles including olfactive components have a glass temperature of >50° C. They are obtainable by continuously adding a monomer component and an olfactive component to an aqueous solution. The aqueous solution comprises a first initiator and an emulsifier. The added components are distributed in the aqueous solution to obtain reaction mixture while the polymerization of the monomer component is started at the first temperature. The liquid monomer component and the olfactive component are added continuously while a second initiator is added dropwise to the reaction mixture and the first temperature is maintained. After terminating the addition of liquid monomer component and the olfactive component the temperature of the reaction mixture is increased to a second temperature and a third initiator is added dropwise.

摘要翻译： 包含嗅觉组分的聚合物纳米颗粒具有> 50℃的玻璃温度。它们可通过将单体组分和嗅觉组分连续添加到水溶液中而获得。 水溶液包含第一引发剂和乳化剂。 添加的组分分布在水溶液中以获得反应混合物，同时单体组分的聚合在第一个温度下开始。 连续加入液体单体组分和嗅觉组分，同时将第二引发剂滴加到反应混合物中并保持第一温度。 在终止液体单体组分和嗅觉组分的加入后，将反应混合物的温度升至第二温度，并滴加第三引发剂。

公开(公告)号：US20070207052A1

公开(公告)日：2007-09-06

申请号：US11684735

申请日：2007-03-12

申请人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

发明人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

IPC分类号： A61L9/00

CPC分类号： B82Y5/00 ,  A61K8/02 ,  A61K2800/413 ,  A61Q13/00 ,  C08F2/44 ,  C11D3/505 ,  C11D17/0039 ,  Y10T428/2984

摘要： The polymeric nanoparticles including olfactive components have a glass temperature of >50° C. They are obtainable by continuously adding a monomer component and an olfactive component to an aqueous solution. The aqueous solution comprises a first initiator and an emulsifier. The added components are distributed in the aqueous solution to obtain reaction mixture while the polymerization of the monomer component is started at the first temperature. The liquid monomer component and the olfactive component are added continuously while a second initiator is added dropwise to the reaction mixture and the first temperature is maintained. After terminating the addition of liquid monomer component and the olfactive component the temperature of the reaction mixture is increased to a second temperature and a third initiator is added dropwise.

摘要翻译： 包含嗅觉组分的聚合物纳米颗粒具有> 50℃的玻璃温度。它们可通过将单体组分和嗅觉组分连续添加到水溶液中而获得。 水溶液包含第一引发剂和乳化剂。 添加的组分分布在水溶液中以获得反应混合物，同时单体组分的聚合在第一个温度下开始。 连续加入液体单体组分和嗅觉组分，同时将第二引发剂滴加到反应混合物中并保持第一温度。 在终止液体单体组分和嗅觉组分的加入后，将反应混合物的温度升至第二温度，并滴加第三引发剂。

公开(公告)号：US07776939B2

公开(公告)日：2010-08-17

申请号：US11684735

申请日：2007-03-12

申请人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

发明人： Christian Quellet ,  Jutta Hotz ,  Marc Balmer

IPC分类号： A61L2/00

CPC分类号： B82Y5/00 ,  A61K8/02 ,  A61K2800/413 ,  A61Q13/00 ,  C08F2/44 ,  C11D3/505 ,  C11D17/0039 ,  Y10T428/2984

摘要： The polymeric nanoparticles including olfactive components have a glass temperature of >50° C. They are obtainable by continuously adding a monomer component and an olfactive component to an aqueous solution. The aqueous solution comprises a first initiator and an emulsifier. The added components are distributed in the aqueous solution to obtain reaction mixture while the polymerization of the monomer component is started at the first temperature. The liquid monomer component and the olfactive component are added continuously while a second initiator is added dropwise to the reaction mixture and the first temperature is maintained. After terminating the addition of liquid monomer component and the olfactive component the temperature of the reaction mixture is increased to a second temperature and a third initiator is added dropwise.

摘要翻译： 包含嗅觉组分的聚合物纳米颗粒具有> 50℃的玻璃温度。它们可通过将单体组分和嗅觉组分连续添加到水溶液中而获得。 水溶液包含第一引发剂和乳化剂。 添加的组分分布在水溶液中以获得反应混合物，同时单体组分的聚合在第一个温度下开始。 连续加入液体单体组分和嗅觉组分，同时将第二引发剂滴加到反应混合物中并保持第一温度。 在终止液体单体组分和嗅觉组分的加入后，将反应混合物的温度升至第二温度，并滴加第三引发剂。