Method, device and computer program product for assessing the disintegration of a dosage form in the gastrointestinal tract
    2.
    发明授权
    Method, device and computer program product for assessing the disintegration of a dosage form in the gastrointestinal tract 有权
    用于评估胃肠道中剂型崩解的方法,装置和计算机程序产品

    公开(公告)号:US09575044B2

    公开(公告)日:2017-02-21

    申请号:US13389304

    申请日:2010-08-06

    申请人: Mans Minekus

    发明人: Mans Minekus

    摘要: The invention relates to a device for assessing the disintegration of a dosage form in the gastrointestinal tract, comprising a wall surrounding a cell for being filled with a fluid and for receiving the dosage form, further comprising a pressurizable compartment arranged exterior to the wall for repeatedly deforming the wall between a first state and a second state wherein the volume of the cell in the first state is larger than in the second state, wherein the device also comprises controlling means for quantitatively controlling a fluid flow from and into the cell, and/or for quantitatively controlling a contact force that the wall exerts on the dosage form.

    摘要翻译: 本发明涉及一种用于评估胃肠道中的剂型崩解的装置,包括围绕细胞的壁,用于填充流体并用于接收剂型,还包括设置在壁外侧的可加压室,用于反复 使第一状态和第二状态之间的壁变形,其中处于第一状态的电池的体积大于第二状态,其中该装置还包括用于定量地控制流入和流入电池的流体流的控制装置,和/ 或用于定量地控制壁施加在剂型上的接触力。

    Digestion system
    3.
    发明授权

    公开(公告)号:US10417938B2

    公开(公告)日:2019-09-17

    申请号:US14123319

    申请日:2012-05-31

    申请人: Mans Minekus

    发明人: Mans Minekus

    摘要: The invention relates to a digestion system for analyzing the intestinal fluid. The system comprises a compartment containing the fluid content and a micro filter for filtering particles in the fluid content having a size beyond the micro range. The system further comprises a pertractor arranged downstream to the micro filter for removing digested lipophilic particles.

    METHOD, DEVICE AND COMPUTER PROGRAM PRODUCT FOR ASSESSING THE DISINTEGRATION OF A DOSAGE FORM IN THE GASTROINTESTINAL TRACT
    4.
    发明申请
    METHOD, DEVICE AND COMPUTER PROGRAM PRODUCT FOR ASSESSING THE DISINTEGRATION OF A DOSAGE FORM IN THE GASTROINTESTINAL TRACT 有权
    方法,设备和计算机程序产品,用于评估胃肠道诱导剂中剂型的分解

    公开(公告)号:US20120279324A1

    公开(公告)日:2012-11-08

    申请号:US13389304

    申请日:2010-08-06

    申请人: Mans Minekus

    发明人: Mans Minekus

    IPC分类号: G01L5/00

    摘要: The invention relates to a device for assessing the disintegration of a dosage form in the gastrointestinal tract, comprising a wall surrounding a cell for being filled with a fluid and for receiving the dosage form, further comprising a pressurizable compartment arranged exterior to the wall for repeatedly deforming the wall between a first state and a second state wherein the volume of the cell in the first state is larger than in the second state, wherein the device also comprises controlling means for quantitatively controlling a fluid flow from and into the cell, and/or for quantitatively controlling a contact force that the wall exerts on the dosage form.

    摘要翻译: 本发明涉及一种用于评估胃肠道中的剂型崩解的装置,包括围绕细胞的壁,用于填充流体并用于接收剂型,还包括设置在壁外侧的可加压室,用于反复 使第一状态和第二状态之间的壁变形,其中处于第一状态的电池的体积大于第二状态,其中该装置还包括用于定量地控制流入和流入电池的流体流的控制装置,和/ 或用于定量地控制壁施加在剂型上的接触力。

    METHOD FOR PREDICTING GLYCAEMIC RESPONSE AND USE THEREOF
    5.
    发明申请
    METHOD FOR PREDICTING GLYCAEMIC RESPONSE AND USE THEREOF 审中-公开
    预测糖化反应的方法及其用途

    公开(公告)号:US20120142039A1

    公开(公告)日:2012-06-07

    申请号:US13377269

    申请日:2010-06-11

    IPC分类号: C12Q1/40 C12Q1/37 C12Q1/34

    CPC分类号: G01N33/66

    摘要: The present invention relates to an in vitro method for predicting the in vivo glycaemic response to carbohydrates in a food. Provided is a method wherein a food is digested in vitro in more than one compartment. Also provided is the use of such a method for determining the suitability of a food for a subject who would benefit from a normalization of blood glucose levels.

    摘要翻译: 本发明涉及用于预测食物中碳水化合物的体内血糖反应的体外方法。 提供了一种其中食物在多于一个隔室中在体外消化的方法。 还提供了使用这种方法来确定将受益于血糖水平正常化的受试者的食物的适合性。

    A FILTRATION SYSTEM
    6.
    发明申请
    A FILTRATION SYSTEM 有权
    过滤系统

    公开(公告)号:US20140374362A1

    公开(公告)日:2014-12-25

    申请号:US14123327

    申请日:2012-05-31

    申请人: Mans Minekus

    发明人: Mans Minekus

    IPC分类号: B01D29/13 B01D29/56

    摘要: The invention relates to a filtration system for filtering a fluid containing solid particles. The filtration system comprising a deformable wall defining a chamber interior to the wall, and a tubular shaped membrane arranged in the chamber. Further, the system is arranged for periodically deforming the chamber wall inwardly and outwardly, respectively, for filtering a fluid that is present in the chamber, exterior to the membrane.

    摘要翻译: 本发明涉及一种用于过滤含固体颗粒的流体的过滤系统。 所述过滤系统包括限定到所述壁的室内部的可变形壁和布置在所述室中的管状膜。 此外,该系统被布置用于分别向内和向外周期性地使腔壁变形,以过滤存在于膜外部的腔室中的流体。

    DIGESTION SYSTEM
    7.
    发明申请
    DIGESTION SYSTEM 有权
    消毒系统

    公开(公告)号:US20140329216A1

    公开(公告)日:2014-11-06

    申请号:US14123319

    申请日:2012-05-31

    申请人: Mans Minekus

    发明人: Mans Minekus

    IPC分类号: G09B23/30

    摘要: The invention relates to a digestion system for analyzing the intestinal fluid. The system comprises a compartment containing the fluid content and a micro filter for filtering particles in the fluid content having a size beyond the micro range. The system further comprises a pertractor arranged downstream to the micro filter for removing digested lipophilic particles.

    摘要翻译: 本发明涉及一种用于分析肠液的消化系统。 该系统包括含有流体含量的隔室和用于过滤具有超出微范围的尺寸的流体内容物中的颗粒的微过滤器。 该系统还包括设置在微过滤器下游的除去器,用于去除消化的亲脂性颗粒。