公开(公告)号：US20220088417A1

公开(公告)日：2022-03-24

申请号：US17545030

申请日：2021-12-08

申请人： THE JOHNS HOPKINS UNIVERSITY ,  Koninklijke Philips NV.

发明人： Joseph Webster Stayman ,  Aswin John Mathews ,  Reuven Levinson

IPC分类号： A61N5/10 ,  G01N23/00 ,  G21K1/10

摘要： The present invention is directed to multiple aperture devices (MADs) for beam shaping in x-ray imaging. Two or more of these binary filters can be placed in an x-ray beam in series to permit a large number of x-ray fluence profiles. However, the relationship between particular MAD designs and the achievable fluence patterns is complex. The present invention includes mathematical and physical models that are used within an optimization framework to find optimal MAD designs. Specifically, given a set of target fluence patterns, the present invention finds, for example, a dual MAD design that is a “best fit” in generating the desired fluence patterns. This process provides a solution for both the design of MAD filters as well as the control actuation that is required (relative motion between MADs) that needs to be specified as part of the operation of a MAD-based fluence field modulation system.

公开(公告)号：US20170332966A1

公开(公告)日：2017-11-23

申请号：US15522371

申请日：2015-10-16

申请人： KONINKLIJKE PHILIPS NV.

发明人： Egbertus Reinier JACOBS ,  Wouter Herman PEETERS ,  Johannes Wilhelmus WEEKAMP ,  Johannes Henricus Maria VAN ROOSMALEN ,  Rick BEZEMER ,  Igor Wilhelmus Franciscus PAULUSSEN ,  Toeno VAN DER SAR

IPC分类号： A61B5/00 ,  A61B5/024 ,  A61B5/1455 ,  A61M16/06

CPC分类号： A61B5/6819 ,  A61B5/02416 ,  A61B5/14542 ,  A61B5/14552 ,  A61B5/6838 ,  A61M16/06

摘要： When measuring SpO2 in a patient, a nasal oximeter is inserted into the patient's nose and comprises a source pad (14) and a detector pad (18) that are positioned at a predetermined location on either side of the nasal septum. The source pad and detector pad are biased toward each other to provide a clamping force on the nasal septum sufficient to permit SpO2 measurement without causing tissue necrosis. Clamping force is supplied by means of a spring type device, an expandable material, or the like.